Secondary hemophagocytic lymphohistiocytosis in SARS-CoV-2 infection
Authors:
Závodná Radka; Šrámková Lucie; Suková Martina; Starý Jan
Authors place of work:
Klinika dětské hematologie a onkologie 2. LF UK a FN Motol
Published in the journal:
Čes-slov Pediat 2022; 77 (1): 43-48.
Category:
Case Report
Summary
Hemophagocytic lymphohistiocytosis (HLH) is heterogeneous disease characterized by uncotrolled proliferation of T lymphocytes and macrophages result of which is overproduction of cytokines and hemophagocytosis. Without adequate therapy this condition could be life-threatening. We present a case of infant with secondary hemophagocytic lymphohistiocytosis in SARS-CoV-2 infection.
Keywords:
pancytopenia – COVID-19 – hemophagocytic lymphohistiocytosis – hepatosplenomegaly
Zdroje
1. Suková M, Mejstříková E, Vodičková E, et al. Hemofagocytující lymfohistiocytóza. Vnitr Lek 2010; 56(2): 157–169.
2. Lima R, Filho CC, Ferreira Filho CM, et al. Hemophagocytic syndrome and COVID-19. [online]. Dostupné na: https:// www.ncbi.nlm.nih.gov/pmc/articles/PMC7347481.
3. Paul La Rosée, AnnaCarin Horne, Melissa Hines, et al. Recommendations for the management of hemophagocytic lymphohistiocytosis in adults. Blood 2019; 133(23): 2465–2477.
4. Rosado FGN, Kim AS. Hemophagocytic Lymphohistiocytosis: An Update on Diagnosis and Pathogenesis. Am J Clin Pathol 2013; 139(6): 713–727.
5. WHO Coronavirus (COVID-19) Dashboard, 2021. [online]. Dostupné na: https://covid19.who.int/.
6. Opoka-Winiarska V, Grywalska E, Roliński J. Could hemophagocytic lymphohistiocytosis be the core issue of severe COVID-19 cases? [online]. Dostupné na: https://doi. org/10.1186/s12916-020-01682-y.
7. David J, Šibíková M, Jonáš J, et al. Závažná komplikace COVID- 19 u dětí: syndrom multisystémové zánětlivé odpovědi. Pediatr Praxi 2021; 22(1): 8–11.
8. Gustine JN, Jones D. Immunopathology of Hyperinflammation in COVID-19. Am J Clin Pathol 2021; 191(1): 4– 17.
9. Retamozo S, Brito-Zerón P, Sisó-Almirall A, et al. Haemophagocytic syndrome and COVID-19. Clin Rheumatol 2021; 40: 1233–1244.
10. Janka GE, Lehmberg K. Hemophagocytic syndromes--an update. Blood Rev 2014; 28(4): 135–42.
11. Máca J, Sklienka P, Reimer P, Holub M. Nová definice sepse (Sepsis-3): cíle, přednosti a kontroverze. [online]. Dostupné na: https://www.prolekare.cz/casopisy/epidemiologie/ 2018-1-12/nova-definice-sepse-sepsis-3-cile-prednosti- -a-kontroverze-63471. (Accessed July 01, 2021).
Štítky
Neonatology Paediatrics General practitioner for children and adolescentsČlánok vyšiel v časopise
Czech-Slovak Pediatrics
2022 Číslo 1
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
- The Importance of Limosilactobacillus reuteri in Administration to Diabetics with Gingivitis
Najčítanejšie v tomto čísle
- Laboratory newborn screening
- Differential diagnosis in paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2
- Z historie pediatrie
- Brief overview of child and adolescent psychopharmacotherapy