Long-term home oxygen therapy for children
Authors:
Krištofová Holeček Tereza; Koucký Václav; Pohunek Petr
Authors place of work:
Pediatrická klinika, 2. lékařská fakulta, Univerzita Karlova a FN Motol, Praha
Published in the journal:
Čes-slov Pediat 2024; 79 (3): 150-155.
Category:
Comprehensive Report
doi:
https://doi.org/10.55095/CSPediatrie2024/018
Summary
Long term home oxygen therapy for children is defined as oxygenotherapy outside hospital environment dedicated for patients with lung diseases, diseases of pulmonary vascular system and diseases of the thoracic wall (ventilation) suffering from chronic respiratory insufficiency of type 1. The main target of a long-term home oxygen therapy in children (LTOT) is to prevent prolonged hypoxia in children with chronic respiratory condition. Prolonged hypoxia can lead to health complications such as pulmonary hypertension, cognitive impairment etc. LTOT enables patients to spend more time at home and improves their quality of life. LTOT is indicated for end-stages of severe pulmonary and sometimes non-pulmonary illnesses, but there are known pathologies such as bronchopulmonary dysplasia or neuroendocrine cell hyperplasia of infancy where the patient is expected to spontaneously wean of oxygen. This review is the first of two articles presenting LTOT in the Czech Republic. The primary focus of this review is to briefly present the pathophysiological mechanisms leading to hypoxemia and to explain the suitability of oxygen therapy based on this knowledge. It then briefly outlines options for detecting hypoxemia in children and the long-term impact of hypoxemia on the children‘s body and health. Moreover, the review discusses the most common diagnoses indicated and potentially treatable by LTOT.
Keywords:
hypoxemia – long-term oxygen therapy in children (LTOT) – detection of hypoxemia – conse-quences of chronic hypoxemia in children – diagnosis indicated for LTOT
Zdroje
Korespondenční adresa:
MUDr. Tereza Holeček Krištofová
V Úvalu 84
150 06 Praha 5
tereza.holecek-kristofova@fnmotol.cz
1. Guyton AC, Hall JE. Textbook of Medical Physiology. Eleventh edition. Elsevier Saunders 2006: 525–532.
2. Nečas E. Patofyziologická fyziologie orgánových systémů, část I. Nakladatelství Karolinum 2006: 271–290.
3. Yildizdaş D, Yapicioğlu H, Yilmaz HL, Sertdemir Y. Correlation of simultaneously obtained capillary, venous, and arterial blood gases of patients in a paediatric intensive care unit. Arch Dis Child 2004; 89(2): 176–
180.
4. Roberts CM, Bugler JR, Melchor R, Hetzel MR,iet al. Value of pulse oximetry in screening for long-term oxygen therapy requirement. Eur Resp J 1993; 6(4): 559.
5. Hayes D, Wilson KC, Krivchenia K, et al. Home oxygen therapy for children. An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med 2019; 199(3): e5–e23.
6. Evans HJ, Gibson NA, Bennett J, et al. British Thoracic Society guideline for diagnosing and monitoring paediatric sleep-disordered breathing. Thorax 2023; 78(Suppl 2): s1–s27.
7. Coté CJ, Goldstein EA, Fuchsman WH, Hoaglin DC. The effect of nail polish on pulse oximetry. Anesth Analg 1988; 67(7): 683–686.
8. Hampson NB. Pulse Oximetry in Severe Carbon Monoxide Poisoning. Chest 1998; 114(4): 1036–1041.
9. Grace RF. Pulse oximetry. Gold standard or false sense of security? Med J Aust 1994516; 160(10).
10. Weitzenblum E, Chaouat A. Hypoxic pulmonary hypertension in man: what minimum daily duration of hypoxaemia is required? Eur Respir J 2001; 18(2): 251–253.
11. Bass JL, Corwin M, Gozal D, et al. The effect of chronic or intermittent hypoxia on cognition in childhood: a review of the evidence. Pediatrics 2004; 114(3): 805–816.
12. Harris MA, Sullivan CE. Sleep pattern and supplementary oxygen requirements in infants with chronic neonatal lung disease. Lancet 1995; 345(8953): 831–832.
13. Aljadeff G, Gozal D, Bailey-Wahl SL, et al. Effects of overnight supplemental oxygen in obstructive sleep apnea in children. Am J Respir Crit Care Med 1996; 153(1): 51–55.
14. Olaithe M, Bucks RS, Hillman DR, Eastwood PR. Cognitive deficits in obstructive sleep apnea: Insights from a meta-review and comparison with deficits observed in COPD, insomnia, and sleep deprivation. Sleep Med Rev 2018; 38: 39–49.
15. Samuels MP, Poets CF, Southall DP. Abnormal hypoxemia after life-threatening events in infants born before term. J Pediatr 1994; 125(3): 441–
446.
16. Niermeyer S, Moore LG. Hypoxic responses in infants. No known mechanism links hypoxia and sudden infant death syndrome. BMJ 1998; 317(7159): 675–676; author reply 677–8.
17. Moyer-Mileur LJ, Nielson DW, Pfeffer KD, et al. Eliminating sleep-associated hypoxemia improves growth in infants with bronchopulmonary dysplasia. Pediatrics 1996; 98(4 Pt 1): 779–783.
18. Groothuis JR, Rosenberg AA. Home oxygen promotes weight gain in infants with bronchopulmonary dysplasia. Am J Dis Child 1987; 141(9): 992–995.
19. Benatar A, Clarke J, Silverman M. Pulmonary hypertension in infants with chronic lung disease: non-invasive evaluation and short term effect of oxygen treatment. Arch Dis Child Fetal Neonatal Ed 1995; 72(1): F14–9.
20. Sekar KC, Duke JC. Sleep apnea and hypoxemia in recently weaned premature infants with and without bronchopulmonary dysplasia. Pediatr Pulmonol 1991; 10(2): 112–116.
21. Baraldi E, Carra S, Vencato F, et al. Home oxygen therapy in infants with bronchopulmonary dysplasia: a prospective study. Eur J Pediatr 1997; 156(11): 878–882.
22. Fan LL, Kozinetz CA. Factors influencing survival in children with chronic interstitial lung disease. Am J Respir Crit Care Med 1997; 156(3 Pt 1): 939–942.
23. Kurland G, Deterding RR, Hagood JS, et al. An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy. Am J Respir Crit Care Med 2013; 188(3): 376–394.
24. Colom AJ, Maffey A, Bournissen FG, Teper A. Pulmonary function of a paediatric cohort of patients with postinfectious bronchiolitis obliterans. A long term follow-up. Thorax 2015; 70(2): 169.
25. Wang B, Cardenas M, Bedoya M, et al. Upregulation of neuropeptides and obstructive airway disorder in infancy: A review with focus on post-RSV wheezing and NEHI. Pediatr Pulmonol 2021; 56(6): 1297–1306.
26. Dervaux M, Thumerelle C, Fabre C, et al. Long-term evolution of neuroendocrine cell hyperplasia of infancy: the FRENCHI findings. Eur J Pediatr 2023; 182(2): 949–956.
27. Balfour-Lynn IM, Field DJ, Gringras P, et al. BTS guidelines for home oxygen in children. Thorax 2009; 64(Suppl 2): ii1–ii26.
28. Zinman R, Corey M, Coates AL, et al. Nocturnal home oxygen in the treatment of hypoxemic cystic fibrosis patients. J Pediatr 1989; 114(3): 368–377.
29. Spier S, Rivlin J, Hughes D, Levison H. The effect of oxygen on sleep, blood gases, and ventilation in cystic fibrosis. Am Rev Respir Dis 1984; 129(5): 712–718.
30. Gozal D. Nocturnal ventilatory support in patients with cystic fibrosis: comparison with supplemental oxygen. Eur Resp J 1997; 10(9): 1999–2003.
31. Nixon PA, Orenstein DM, Curtis SE, Ross EA. Oxygen supplementation during exercise in cystic fibrosis. Am Rev Respir Dis 1990; 142(4): 807–
811.
32. Young AC, Wilson JW, Kotsimbos TC, Naughton MT. Randomised placebo controlled trial of non-invasive ventilation for hypercapnia in cystic fibrosis. Thorax 2008; 63(1): 72–77.
33. Roy R, Couriel JM. Secondary pulmonary hypertension. Paediatr Respir Rev 2006; 7(1): 36–44.
34. Higenbottam T, Cremona G. Acute and chronic hypoxic pulmonary hypertension. Eur Respir J 1993; 6(8): 1207–1212.
35. Bowyer JJ, Busst CM, Denison DM, Shinebourne EA. Effect of long term oxygen treatment at home in children with pulmonary vascular disease. Br Heart J 1986; 55(4): 385–390.
36. Marcus CL, Carroll JL, Bamford O, et al. Supplemental oxygen during sleep in children with sleep-disordered breathing. Am J Respir Crit Care Med 1995; 152(4 Pt 1): 1297–1301.
Štítky
Neonatology Paediatrics General practitioner for children and adolescentsČlánok vyšiel v časopise
Czech-Slovak Pediatrics
2024 Číslo 3
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
- The Importance of Limosilactobacillus reuteri in Administration to Diabetics with Gingivitis
Najčítanejšie v tomto čísle
- Eating disorders in childhood and adolescence
- Zemřel MUDr. Pavel Frühauf, CSc.
- Vitamin B12 deficiency – another challenge to expand newborn laboratory screening?
- Laboratory newborn screening in the Czech Republic: results in 2010–2022 period