Malabsorption syndromes

Česká verzia

Authors: Ambrozová Martina ^1,2; Hrunka Matěj ^1,2; Jabandžiev Petr ^1,2,3
Authors place of work: Pediatrická klinika, Fakultní nemocnice Brno ¹; Lékařská fakulta, Masarykova univerzita, Brno ²; RECETOX, Přírodovědecká, fakulta, Masarykova univerzita, Brno ³
Published in the journal: Čes-slov Pediat 2024; 79 (4): 226-232.
Category: Chapters for Specialization in Pediatrics
doi: https://doi.org/10.55095/CSPediatrie2024/037

Summary

Malabsorption syndromes represent a large group of diseases characterized by impaired intraluminal digestion or nutrient absorption and typically manifest as diarrhea, steatorrhea, bloating and/or failure to thrive. Some diseases may be accompanied by specific symptoms such as oedema, digital clubbing and perianal exanthema. This article aims to classify malabsorption syndromes based on recent findings and summarize their etiology, etiopathogenesis and clinical manifestation. We review current diagnostic and therapeutic approaches. In accordance with the section in which the text will be published, frequent nosological entities will be discussed. Rarer diseases (such as malabsorption due to graft versus host disease) will be mentioned briefly, we direct readers to relevant and detailed sources.

Keywords:

malabsorption syndrome – exocrine pancreatic insufficiency – Celiac disease – short bowel syndrome – chronic cholestasis – protein-losing enteropathy – lactase deficiency – small intes-tinal bacterial overgrowth

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