Potential use of immunohistochemistry for diagnosis precision in historic paraffin blocks
Authors:
Aleš Ryška 1
; Jan Betlach 2
Published in the journal:
Čes.-slov. Patol., 55, 2019, No. 2, p. 122-125
Category:
Original Articles
Summary
Authors present an autopsy case report where the immunohistochemical examination of tissues archived as paraffin blocks for more than 60 years enabled to identify the most probable primary origin of disseminated poorly differentiated adenocarcinoma. The potential issues caused by so called antigen decay and limitations of immunohistochemistry in archive material are discussed.
Keywords:
immunohistochemistry – paraffin block – archive tissue – antigen decay
Zdroje
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Štítky
Anatomical pathology Forensic medical examiner ToxicologyČlánok vyšiel v časopise
Czecho-Slovak Pathology
2019 Číslo 2
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