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A case report: Acute kidney injury with progression to chronicity in an eldery woman


Authors: Olga Snížková 1;  Karolína Krátká 2;  Martin Havrda 2;  Ivan Rychlík 2;  Mayara Elisa Knížek Bonatto 2;  Eva Honsová 1
Authors place of work: Aeskulab Patologie, k. s., Praha 1;  Interní klinika 3. lékařské fakulty Univerzity Karlovy a Fakultní nemocnice Královské Vinohrady, Praha 2
Published in the journal: Čes.-slov. Patol., 59, 2023, No. 2, p. 80-84
Category: Original Articles

Summary

Acute renal failure in elderly patients can be caused by a wide spectrum of diseases that usually have a cause outside the kidney. The most common causes include renal impairment as part of ANCA vasculitis, another category includes clonal plasmatic cell disease with light chain cast nephropathy; and there also exists an increasing number of drug-induced tubulointerstial damage. We present a case of iatrogenic less common form of acute failure in a 73-year-old woman, who did not suffer from any serious disease until then. Although the biopsy helped to determine the cause of the failure and thus affect subsequent therapy, the function did not return to the previous state and the patient progressed to CKD G3bA1 with serum creatinine values of around 170-140 μmol/l.

Keywords:

statins – drug toxicity – rhabdomyolysis – acute kidney injury – renal biopsy – renal intratubular casts


Zdroje

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Štítky
Anatomical pathology Forensic medical examiner Toxicology
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