DNA diagnostics of the most common forms of monogenic diabetes in Slovakia

Česká verzia

Authors: Daniela Gašperíková ¹; Terézia Valkovičová ¹; Martina Škopková ¹; Juraj Staník ^1,2
Authors place of work: DIABGENE & Ústav experimentálnej endokrinológie, Biomedicínske centrum SAV, Bratislava ¹; Detská klinika LF UK a NÚDCH, Bratislava ²
Published in the journal: Diab Obez 2019; 19(37): 13-19
Category: Reviews

Summary

Monogenic diabetes mellitus is a type of diabetes, where genetics without any other factors is strong enough to cause the disease. It is an etiologically very heterogeneous group of diseases, with more than 20 causal genes. Due to clinical similarity to major types of diabetes, the differentiation and definitive diagnosis is allowed only by methods of DNA analysis. Identifying people with monogenic diabetes is also important for specific treatment and prognosis of diabetes.

Received 23. 4. 2019

Accepted 8. 5. 2019

Keywords:

DNA analysis – MODY monogenic diabetes mellitus

Zdroje

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