Possibilities of using genetic knowledge in type 2 diabetes in clinical practice

Česká verzia

Authors: Ivan Tkáč
Published in the journal: Forum Diab 2019; 8(2): 150-152
Category:

Summary

The use of genetic knowledge has been used in the clinical practice of diabetology for several decades. These findings have so far been mainly used in the diagnosis and treatment of monogenic types of diabetes. Although genome-wide association studies have identified more than 100 gene variants associated with type 2 diabetes, the translation of these findings into clinical practice is still limited. In this paper, we present two examples of the transfer of genetic knowledge into clinical practice regarding the pharmacogenetics of metformin therapy and the possibility of using genetic scores to assess cardiovascular risk in patients with type 2 diabetes.

Keywords:

cardiovascular genetic score – genetics of type 2 diabetes – pharmacogenetics of metformin

Zdroje

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