Metformin treatment and its effect on survival in patients with type 2 diabetes mellitus

Česká verzia

Authors: Andrej Dukát ¹; Juraj Payer ¹; Ján Kyselovič ¹; Milan Kriška ²; Patrik Valent ¹; Peter Jackuliak ¹
Authors place of work: V. interná klinika LF UK a UNB, Nemocnica Ružinov, Bratislava ¹; Ústav farmakológie a klinickej farmakológie LF UK v Bratislave ²
Published in the journal: Forum Diab 2023; 12(3): 103-105
Category: Review Article

Summary

Longitudinal monitoring of metformin treatment of patients with type-2 diabetes mellitus leads to the improvement of their survival. Multicentric follow-up in four centers of the United Kingdom during years 2016–2021 evaluated coronary microvascular function in relation to the metformin therapy. Significant improvement of myocardial perfusion reserve lead to better prognosis of the patients with type-2 diabetes mellitus. Measurement of myocardial perfusion reserve is the better measure for endothelial function, than myocardial perfusion flow.

Keywords:

metformin – mellitus – microcirculation – myocardial function – prognosis

Zdroje

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