Obesity – overview of contemporary knowledge and its role in the context of selected cardiovascular diseases

Česká verzia

Authors: Jakub Jurica ¹; Martin Jozef Péč ¹; Monika Péčová ²; Boris Focko ¹; Tomáš Bolek ¹; Patrícia Kleinová ^1,3; Matej Samoš ¹; Marián Mokáň ¹
Authors place of work: I. interná klinika JLF UK a UNM, Martin ¹; Národné centrum hemostázy a trombózy KHaT, JLF UK a UNM, Martin ²; Transplantačno–nefrologické oddelenie UNM, Martin ³
Published in the journal: Forum Diab 2024; 13(2): 96-101
Category: Review Article

Summary

Obesity is a chronic metabolic disease, which is currently regarded as a new pandemic with a significant impact on the morbidity and mortality of population, while its prevalence is rising at an alarming rate. It is associated with cardiovascular diseases such as atrial fibrillation, syndrome of chronic heart failure as well as arterial hypertension. Even though the diagnostic process of obesity has not changed, and the value of Body mass index is still the main criterion, therapy has made significant progress incorporating new pharmacological agents including glucagon like peptide 1 receptor agonists. Clinical management of obese patients is still insufficient at present and receives little attention, it is usually initiated in late stages when complications have already developed, although clinical care for obese patients is not restricted to the obesitologist or endocrinologist/diabetologist, but it can be also managed by internists and general practitioners. Only a small percentage of patients with obesity receives recommended therapy and even fewer patients are followed up long-term on a regular basis to maintain the decreased weight. The aim of this article is to provide an insight into obesity as an independent disease with its own complications, diagnostic and therapeutic algorithm in the light of new evidence and to highlight the role of obesity and its specific features in the context of selected cardiovascular diseases.

Keywords:

obesity – cardiovascular diseases – glucagon like peptide 1 receptor agonists

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