Non-steroidal anti-inflammatory drugs induced colopathy, mimicking Crohn’s disease
Authors:
L. Gombošová 1; M. Zakuciová 1; E. Veseliny 1; I. Drahovská 2; M. Švajdler 3; J. Bober 4; M. Oetterová 1
Authors place of work:
I. Interná klinika, Univerzitná nemocnica L. Pasteura, Košice, 2Klinika rádiodiagnostiky a zobrazovacích metód, Univerzitná nemocnica L. Pasteura, Košice, 3Oddelenie patológie, Univerzitná nemocnica L. Pasteura, Košice, 4I. chirurgická klinika, Univerzitn
1
Published in the journal:
Gastroent Hepatol 2010; 64(6): 15-20
Category:
Case Report
Summary
The authors describe the case of a 47-year-old woman with rheumatoid arthritis who took, in the long term, nonsteroidal anti-inflammatory drugs (NSAID). Her state was complicated by sideropenic anaemia with high inflammatory humoral response during complete rheumatological therapy. She was examined by a gastroenterologist. Colonoscopy revealed severe colitis, which was preliminarily evaluated as a Crohn’s disease and a complete therapy including infliximab was administered. However, her condition did not improve and repeated colonoscopy was carried out. This investigation revealed a worse finding with severe continuous ulcerations of the large bowel. The diagnosis was re-evaluated for NSAID induced colopathy. The previous therapy was stopped and colectomy with ileosigmoideostomy was performed. After surgery the patient was feeling well, had no anaemia, and the humoral anti-inflammatory response decreased. The authors present a review of NSAID induced colopathy which can mimic Crohn’s disease.
Key words:
colopathy – non-steroidal anti-inflammatory drugs (NSAID) – Crohn’s disease – rheumatoid arthritis
Zdroje
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Štítky
Paediatric gastroenterology Gastroenterology and hepatology SurgeryČlánok vyšiel v časopise
Gastroenterology and Hepatology
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