Differential diagnosis of autoimmune form of the pancreatitis and pancreatic adenocarcinoma

Česká verzia

Authors: Petr Dítě ¹ ; Magdalena Uvírová ² ; M. Bojková ¹; I. Novotný ³; J. Dvořáčková ⁴; Bohuslav Kianička ⁵ ; H. Nechutová ⁵; L. Dovrtělová ⁶; K. Floreanová ⁷; Arnošt Martínek ¹
Authors place of work: Akademické centrum gastroenterologie, Interní klinika LF OU a FN Ostrava ¹; CGB Laboratoř Agel, Ostrava ²; Masarykův onkologický ústav, Brno ³; Ústav patologie LF OU a FN Ostrava ⁴; II. interní klinika FN u sv. Anny, Brno ⁵; Katedra podpory zdraví, FSS MU, Brno ⁶; Interní gastroenterologická klinika LF MU a FN Brno ⁷
Published in the journal: Gastroent Hepatol 2014; 68(6): 492-496
Category: Gastrointestinal Oncology: Review Article
doi: https://doi.org/10.14735/amgh2014492

Summary

Differencial diagnosis of autoimmune pancreatitis and pancreatic carcinoma is usaully quite difficult procedure. In clinical practice a combination of clinical disease course and response to the therapy, serological markers, imaging methods and histology are used. The team-work and close cooperation with dedicted experts from other specialisation are absolutely needed.

Key words:
autoimmune pancreatitis – autoimmune diseases – pancreatic carcinoma

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
5. 9. 2014

Accepted:
7. 10. 2014

Zdroje

1. Umehara H, Okazaki K, Masaki Y et al. Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011. Mod Rheumatol 2012; 22(1): 22–30. doi: 10.1007/s10165-011-0571-z.

2. Umehara H, Okazaki K, Masaki Y et al. A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details. Mod Rheumatol 2012; 22(1): 1–14. doi: 10.1007/s10165-011-0508-6.

3. Vlachou PA, Khalili K, Jang HJ et al. IgG4-related sclerosing disease: autoimmune pancreatitis and extrapancreatic manifestation. Radiographics 2011; 31(5): 1379–1402. doi: 10.1148/rg.315105735.

4. Kamisawa T, Egawa N, Nakajima H et al. Clinical difficulties in the differentiation of autoimmune pancreatitis and pancreatic carcinoma. Am J Gastroenterol 2003; 98(12): 2694–2699.

5. Shimosegawa T, Chari ST, Frulloni L et al. International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology. Pancreas 2011; 40(3): 352–358. doi: 10.1097/MPA.0b013e3182142fd2.

6. Hamano H, Kawa S, Horiuchi A et al. High serum IgG4 concentrations in patiens with sclerosing pancreatitis. N Engl J Med 2001; 344(10): 732–738.

7. Ghazale A, Chari ST, Smyrk TC et al. Value of serum IgG4 in diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancer. Am J Gastroenterol 2007; 102(8): 1646–1653.

8. Raina A, Krasinskas A, Greer JB et al. Serum immunoglobulin G fraction 4 levels in pancreatic cancer: elevations not associated with autoimmune pancreatitis. Arch Pathol Lab Med 2008; 132(1): 48–53. doi: 10.1043/1543-2165(2008)132[48:SIGFLI]2.0.CO;2.

9. Kamisawa T, Chen PY, Tu Y et al. Pancreatic cancer with a high serum IgG4 concentration. World J Gastroenterol 2006; 12(38): 6225–6228.

10. Sugumar A, Takahashi NB, Chari ST et al. Distinguishing pancreatic cancer from autoimmune pancreatitis. Curr Gastroenterol Rep 2010; 12(2): 91–97. doi: 10.1007/s11894-010-0098-z.

11. Psarras K, Baltatzis ME, Pavlidis ET et al. Autoimmune pancreatitis versus pancreatic cancer: a comprehensive review with emphasis on differential diagnosis. Hepatobiliary Pancreat Dis Int 2011; 10(5): 465–473.

12. Wakabayashi T, Kawaura Y, Satomura Y et al. Clinical and imaging features of autoimmune pancreatitis with focal pancreatic swelling or mass formation: comparison with so-called tumor-forming pancreatitis and pancreatic carcinoma. Am J Gastroenterol 2003; 98(12): 2679–2687.

13. Dite P, Novotny I, Kala Z et al. The serological positivity of immunoglobulin G4 in patients with autoimmune pancreatitis and pancreatic carcinoma. [In press].

14. Yamamoto M, Takahashi H, Tabeya T et al. Risk of malignancies in IgG4-related disease. Mod Rheumatol 2012; 22(3): 414–418. doi: 10.1007/s10165-011-0520-x.

15. Shiokawa M, Kodama Y, Yoshimura K et al. Risk of cancer in patients with autoimmune pancreatitis. Am J Gastroenterol 2013; 108(4): 610–617. doi: 10.1038/ajg.2012.465.

16. Pezzilli R, Vecchiarelli S, Di Marco MC et al. Pancreatic ductal adenocarcinoma associated with autoimmune pancreatitis. Case Rep Gastroenterol 2011; 5(2): 378–385. doi: 10.1159/000330291.

17. Loos M, Esposito I, Hedderich DM et al. Autoimmune pancreatitis complicated by carcinoma of the pancreatobiliary system: a case report and review of the literature. Pancreas 2011; 40(1): 151–154. doi: 10.1097/MPA.0b013e3181f74a13.

18. Witkiewicz AK, Kennedy EP, Kennyon I et al. Synchronous autoimmune pancreatitis and infiltrating pancreatic ductal adenocarcinoma: case report and review of the literature. Hum Pathol 2008; 39(10): 1548–1551. doi: 10.1016/j.humpath.2008.01.021.

19. Kawamoto S, Siegelman SS, Hruban RH et al. Lymphoplasmacytic sclerosing pancreatitis (autoimmune pancreatitis), evaluation with multidetector CT. Radiographics 2008; 28(1): 157–170. doi: 10.1148/rg.281065188.

20. Takahashi N, Fletcher JG, Fidler JL et al. Dual-phase CT of autoimmune pancreatitis: a multireader study. Am J Roentgenol 2008; 190(2): 280–286. doi: 10.2214/AJR.07.2309.

21. Mariappan YK, Glaser KJ, Ehman RL. Magnetic resonance elastography: a review. Clin Anat 2010; 23(5): 497–511. doi: 10.1002/ca.21006.

22. Otsuki M, Chung JB, Okazaki K et al. Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symopsium on autoimmune pancreatitis. J Gastroenterol 2008; 43(6): 403–408. doi: 10.1007/s00535-008-2205-6.

23. Sugumar A, Levy MJ, Kamisawa T et al. Endoscopic retrograde pancreatography criteria to diagnose autoimmune pancreatitis: an international multicentre study. Gut 2011; 60(5): 666–670. doi: 10.1136/gut.2010.207951.

24. Kamisawa T, Imai M, Yui Chen P et al. Strategy for differentiating autoimmune pancreatitis from pancreatic cancer. Pancreas 2008; 37(3): e62–e67. doi: 10.1097/MPA.0b013e318175e3a0.

25. Rebours V, Le Baleur Y, Cazals-Hatem D et al. Immunoiglobulin G4 immunostaining of gastric, duodenal, or colonic biopsies is not helpful for the diagnosis of autoimmune pancreatitis. Clin Gastroenterol Hepatol 2012; 10(1): 91–94. doi: 10.1016/j.cgh.2011.09.008.

26. Kim MH, Moon SH, Kamisawa T et al. Major duodenal papilla in autoimmune pancreatitis. Dig Surg 2010; 27(2): 110–114. doi: 10.1159/000286573.

27. Chari ST, Kloeppel G, Zhang L et al. Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document. Pancreas 2010; 39(5): 549–554. doi: 10.1097/MPA.0b013e3181e4d9e5.

28. Naitoh I, Nakazawa T, Ohara H et al. Clinical singnificance of extrapancreatic lesions in autoimmune pancreatitis. Pancreas 2010; 39(1): e1–e5. doi: 10.1097/MPA.0b013e3181bd64a1.

29. Chari ST, Takahashi N, Levy MJ et al. A diagnostic strategy to distinguish autoimmune pancreatitis from pancreatic cancer. Clin Gastroenterol Hepatol 2009; 7(10): 1097–1103. doi: 10.1016/j.cgh.2009.04.020.

30. Chari ST, Smyrk TC, Levy MJ et al. Diagnosis of autoimmune pancreatitis: the Mayo Clinic experience. Clin Gastroenterol Hepatol 2006; 4(8): 1010–1016.

31. Agrawal S, Daruwala C, Khurana J. Distinguishing autoimmune pancreatitis from pancreatobiliary cancers: current strategy. Ann Surg 2012; 255(2): 248–258. doi: 10.1097/SLA.0b013e3182324549.

32. Khalid A, Dewitt J, Ohori NP et al. EUS-FNA mutational analysis in differentiating autoimmune pancreatitis and pancreatic cancer. Pancreatology 2011; 11(5): 482–486. doi: 10.1159/000331505.

33. Kim JH, Kim MH, Byun JH et al. Diagnostic strategy for differentiating autoimmune pancreatitis from pancreatic cancer: is an endoscopic retrograde pancreatography essential? Pancreas 2012; 41: 639–647.

34. Nishino T, Oyama H, Toki F et al. Differentiation between autoimmune pancreatitis and pancreatic carcinoma based on endoscopic retrograde cholangiopancreatography findings. J Gastroenterol 2010; 45(9): 988–996. doi: 10.1007/s00535-010-0250-4.