Olysio^® (simeprevir)

Česká verzia

Authors: I. Hejlová
Authors place of work: Klinika hepatogastroenterologie, Transplantcentrum, IKEM, Praha
Published in the journal: Gastroent Hepatol 2016; 70(4): 368-370
Category: Drug Profile
doi: https://doi.org/10.14735/amgh2016368

Zdroje

1. Souhrn údajů o přípravku. Olysio^® 150 mg cps. [online]. Dostupné z: www.sukl.cz. Citováno 30. 6. 2016.

2. Jacobson IM, Dore GJ, Foster GR et al. Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet 2014; 384(9941): 403– 413. doi: 10.1016/ S0140-6736(14)60494-3.

3. Kwo P, Gitlin N, Nahass R et al. Simeprevir plus sofosbuvir (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study. Hepatology 2016; 64(2): 370– 380. doi: 10.1002/ hep.28467.

4. Lawitz E, Matusow G, DeJesus E. Simeprevir plus sofosbuvir in patients with chronic hepatitis C virus genotype 1 infection and cirrhosis: a phase 3 study (OPTIMIST-2). Hepatology 2016; 64(2): 360– 369. doi: 10.1002/ hep.28422.

5. Manns M, Marcellin P, Poordad F et al.

Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3

trial. Lancet 2014; 384(9941): 414– 426. doi: 10.1016/ S0140-6736(14)60538-9.

6. Forns X, Lawitz E, Zeuzem S et al. Simeprevir with peginterferon and ribavirin leads to high rates of SVR in patients with HCV genotype 1 who relapsed after previous therapy: a phase 3 trial. Gastroenterology 2014; 146(7): 1669– 1679. doi: 10.1053/ j.gastro.2014.02.051.

7. El Raziky M, Gamil M, Hammad R et al. Treatment of hepatitis C genotype 4 patients with simeprevir and sofosbuvir: results from a Phase IIa, partially randomised, open-label trial conducted in Egypt (OSIRIS). Poster presented at: American Association for the Study of Liver Disease (AASLD). 15 November 2015: San Francisco, USA.

8. Buti M. Simeprevir plus sofosbuvir for hepatitis C virus genotype 4 infection: a Phase III, open-label study. Presented at: EASL International Liver Congress (ILC). 13– 17 April 2016: Barcelona, Spain.

9. Moreno C, Hezode C, Marcellin P et al. Efficacy and safety of simeprevir with PegIFN/ribavirin in naïve or experienced patients infected with chronic HCV genotype 4. J Hepatol 2015; 62(5): 1047– 1055. doi: 10.1016/ j.jhep.2014.12.031.

10. Willemse SB, Baak LC, Kuiken SD et al. Sofosbuvir plus simeprevir for the treatment of HCV genotype 4 patients with advanced fibrosis or compensated cirrhosis is highly efficacious in real life. J Viral Hepat 2016. In press. doi: 10.1111/ jvh.12567.