#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Malignant melanoma metastases in the gastrointestinal tract with unknown primary site


Authors: F. Shon 1;  M. Kočová 2;  Z. Štiková 3
Authors place of work: Gastroenterologické oddělení, Nemocnice České Budějovice, a.  s. 1;  Onkologické oddělení, Nemocnice České Budějovice, a.  s. 2;  Patologické oddělení, Nemocnice České Budějovice, a.  s. 3
Published in the journal: Gastroent Hepatol 2016; 70(5): 418-421
Category: Gastrointestinal Oncology: Case Report
doi: https://doi.org/10.14735/amgh2016csgh.info12

Summary

A case of a 73-year-old man with a history of multiple cutaneous tumors treated by surgical excision is presented. The patient was thoroughly followed up by a dermatologist without any sign of recurrence. However, the patient was referred for colonoscopy after showing signs of anorexia and weight loss. Endoscopy and further examination revealed a malignant melanoma with an unknown primary site that had metastasized to the gastrointestinal tract and other organs. The article summarizes information about this aggressive disease, which is one of the most common causes of gastrointestinal metastases.

Key words:
melanoma – neoplasm metastasis – gastrointestinal tract – endoscopy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
4. 4. 2016

Accepted:
17. 5. 2016


Zdroje

1. SVOD analýza. Incidence a mortalita – vývoj v čase. Brno: Masarykova univerzita 2005. [online]. Dostupné z: www.svod.cz.

2. Panagiotou I, Brountzos EN, Bafaloukos D et al. Malignant melanoma metastatic to the gastrointestinal tract. Melanoma Res 2002; 12 (2): 169–173.

3. Schlagenhauff B, Stroebel W, Ellwanger U et al. Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma: recommendations for initial staging examinations. Cancer 1997; 80 (1): 60–65.

4. Liang KV, Sanderson SO, Nowakowski GS et al. Metastatic malignant melanoma of the gastrointestinal tract. Mayo Clin Proc 2006; 81 (4): 511–516. doi: 10.4065/ 81.4.511.

5. Lakomý R et al. Současné možnosti léčby pokročilého a metastatického maligního melanomu. Onkologie 2013; 7 (2): 65–68.

6. Hu-Lieskovan S, Robert L, Homet Moreno et al. Combining targeted therapy with immunotherapy in BRAF-mutant melanoma: promise and challenges. J Clin Oncol 2014; 32 (21): 2248–2254. doi: 10.1200/JCO.2013.52.1377.

7. Wornom IL 3rd, Smith JW, Soong SJ et al. Surgery as palliative treatment for distant metastases of melanoma. Ann Surg 1986; 204 (2): 181–185.

8. Taal BG, Westerman H, Boot H et al. Clinical and endoscopic features of melanoma metastases in the upper GI tract. Gastrointest Endosc 1999; 50 (2): 261–263.

Štítky
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Článok vyšiel v časopise

Gastroenterology and Hepatology

Číslo 5

2016 Číslo 5
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#