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Ustekinumab – a new biological therapy for patients with Crohn’s disease


Authors: M. Lukáš
Authors place of work: Klinické a výzkumné centrum pro střevní záněty ISCARE I. V. F. a.  s., Praha
Published in the journal: Gastroent Hepatol 2017; 71(2): 178-180
Category: Drug Profile
doi: https://doi.org/doi: 10.14735/amgh2017178


Zdroje

1. Feagan BG, Sandborn WJ, Gasink C et al. Ustekinumab as induction and maintenance therapy for Crohn’s disease. N Engl J Med 2016; 375 (20): 1946–1960.

2. Sandborn WJ, Feagan BG, Fedorak RN et al. A randomized trial of ustekinumab a human interleukin 12/23 monoclonal antibody in patients with moderate to severe Crohn’s disease. Gastroenterology 2008; 135 (4): 1130–1141. doi: 10.1053/j.gastro.2008.07.014.

3. Sandborn WJ, Gasink C, Gao LL et al. Ustekinumab induction and maintenance therapy in refractory Crohn’s disease. N Engl J Med 2012; 367 (16): 1519–1528. doi: 10.1056/NEJMoa1203572.

4. Battat R, Kopylov U, Bessissow T et al. Association of ustekinumab trough concentration with clinical, biochemical and endoscopic outcome. Presented at: 11th Congress of ECCO, Amsterdam 2016.

5. European medicines agency. Stelara®. [online]. Available from: http: //www.ema.europa.eu.

Štítky
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Článok vyšiel v časopise

Gastroenterology and Hepatology

Číslo 2

2017 Číslo 2
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