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GNET of small bowell


Authors: Málková Š. 1;  Papík Z. 1;  Navrátilová B. 2
Authors place of work: Endoskopické centrum, Oblastní nemocnice Náchod a. s. 1;  Patologické oddělení, Oblastní nemocnice Náchod a. s. 2
Published in the journal: Gastroent Hepatol 2020; 74(6): 543-546
Category: Digestive Endoscopy: Case Report
doi: https://doi.org/10.48095/ccgh2020543

Summary

Summary: The case report presents a rare malignant tumor of the duodenojejunal junction with generalization in an elderly polymorbid woman, which showed symptoms of high ileus. The tumor infiltrated almost the entire width of the wall with the exception of the mucosa layer and metastatically affected the lymph nodes and the wall and visceral peritoneum. The dia gnosis was determined after surgical resection based on histological and immunohistochemical examinations which proved the positivity of S100 protein and  synaptophysin.

Keywords:

tumor of small bowel – high ileus – immunohistochemistry – GNET


Zdroje

1. Zambrano E, Reyes-Mugica M, Franchi A et al. An osteoclast-rich tumor of the gastrointestinal tract with features resembling clear cell sarcoma of soft parts: reports of 6 cases of a GIST simulator. Int J Surg Pathol 2003; 11 (2): 75–81. doi: 10.1177/106689690301100202.

2. Huang GX, Chen QY, Zhong LL et al. Primary malignant gastrointestinal neuroectodermal tumor occuring in the ileum with intra-abdominal granulamotous nodules: A case report and review of the literature. Oncol Lett 2019; 17 (4): 3899–3909. doi: 10.3892/o1.2019.10060.

3. Alyosef MJ, Alratroot JA, ElSharkawy T et al. Malignant gastrointestinal neuroectodermal tumor: a case report and review of the literature. Dia gn Pathol 2017; 12 (1): 29. doi: 10.1186/s13000-017-0620-9.

4. Singh D, Atieh MK, Russell MA et al. Malignant Gastrointestinal Neuroectodermal Tumor (GNET) with prolonged disease-free survival after platinum-based chemotherapy. Case Rep Oncol Med 2020; 2020: 8880202. doi: 10.1155/2020/8880202.

5. Wang J, Thway K. Clear cell sarcoma-like tumor of the gastrointestinal tract: an evolving entity. Arch Pathol Lab Med 2015; 139 (3):  407–412. doi: 10.5858/arpa.2013-0547-RS.

Štítky
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Článok vyšiel v časopise

Gastroenterology and Hepatology

Číslo 6

2020 Číslo 6
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