Complicated course of IBD in pregnancy
Authors:
V. Štěpánek 1; Z. Šerclová 2; M. Kasalický 3; M. Bortlík- 4 6
Authors place of work:
Gastroenterologické oddělení, Nemocnice České Budějovice, a. s.
1; Klinické a výzkumné centrum pro střevní záněty, Klinické centrum ISCARE a. s. a 1. LF UK v Praze
2; Chirurgická klinika 2. LF UK a ÚVN Praha
3; Interní klinika 1. LF UK a ÚVN Praha
4; Farmakologický ústav 1. LF UK, Praha
5; ZSF JČU v Českých Budějovicích, ZSF JČU, České Budějovice
6
Published in the journal:
Gastroent Hepatol 2023; 77(1): 30-33
Category:
doi:
https://doi.org/10.48095/ccgh202330
Summary
We present a case report of a young female patient with complicated course of inflammatory bowel disease with severe luminal, as well as perianal symptoms. The patient was initially diagnosed with ulcerative colitis and underwent proctocolectomy with ileopouch-anal anastomosis. One year after oostomy closure she got pregnant and, at the same time, she developed perianal abscess and fistula. The diagnosis was thus changed to Crohn’s disease. During pregnancy, she underwent repeated perianal fistula drainages, surgical revision of ileus and treatment with ustekinumab was started. The patient delivered a healthy boy in November 2022 at 38th gestational week.
Keywords:
ustekinumab – Crohn’s disease – pregnancy – perianal Crohn’s disease
Zdroje
1. Mitrova K, Pipek B, Bortlik M et al. Safety of Ustekinumab and Vedolizumab During Pregnancy-Pregnancy, Neonatal, and Infant Outcome: A Prospective Multicentre Study. J Crohns Colitis 2022; 16 (12): 1808–1815. doi: 10.1093/ecco-jcc/jjac086.
2. Chaparro M, Kunovský L, Aguas M et al. Surgery due to Inflammatory Bowel Disease During Pregnancy: Mothers and Offspring Outcomes From an ECCO Confer Multicentre Case Series [Scar Study]. J Crohns Colitis 2022; 16 (9): 1428–1435. doi: 10.1093/ecco-jcc/jjac 050.
3. Wetwittayakhlang P, Gonczi L, Lakatos L et al. Long-term Colectomy rates of Ulcerative Colitis over 40-year of Different Therapeutic eras – Results from Western Hungarian Population-based Inception Cohort between 1977–2020. J Crohns Colitis 2022; jjac188. doi: 10.1093/ecco-jcc/jjac188.
4. Atia O, Orlanski-Meyer E, Lujan R et al. Colectomy Rates did not Decrease in Paediatric- and Adult-Onset Ulcerative Colitis During the Biologics Era: A Nationwide Study From the epi-IIRN. J Crohns Colitis 2022; 16 (5): 796–803. doi: 10.1093/ecco-jcc/jjab210.
5. Jarchin L, Spencer EA, Khaitov S et al. De Novo Crohn’s Disease of the Pouch in Children Undergoing Ileal Pouch-Anal Anastomosis for Ulcerative Colitis. J Pediatr Gastroenterol Nutr 2019; 69 (4): 455–460. doi: 10.1097/ MPG.0000000000002406.
6. Zaghiyan K, Kamiński JP, Barmparas G et al. De novo Crohn‘s Disease after Ileal Pouch-Anal Anastomosis for Ulcerative Colitis and Inflammatory Bowel Disease Unclassified: Long-Term Follow-Up of a Prospective Inflammatory Bowel Disease Registry. Am Surg 2016; 82 (10): 977–981.
7. van der Woude CJ, Ardizzone S, Bengtson MB et al. The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease. J Crohns Colitis 2015; 9 (2): 107–124. doi: 10.1093/ecco-jcc/jju 006.
Štítky
Paediatric gastroenterology Gastroenterology and hepatology SurgeryČlánok vyšiel v časopise
Gastroenterology and Hepatology
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