Quality of life of patients after orthotopic liver transplantation performed for alcoholic cirrhosis
Authors:
M. Česneková 1,2,3; J. Vacek 2
Authors place of work:
Stomatologická klinika 1. LF UK a VFN, Praha, Přednosta: prof. MUDr. René Foltán, Ph. D., FEBOMFS
1; Klinika adiktologie 1. LF UK a VFN, Praha, Přednosta: prof. PhDr. Michal Miovský, Ph. D.
2; Aditea, s. r. o., centrum osobního rozvoje
3
Published in the journal:
Prakt. Lék. 2021; 101(6): 317-326
Category:
Of different specialties
Summary
Excessive and regular alcohol consumption affects negatively the whole organism and the organ that is damaged most often is liver. A whole range of diseases, from the lighter forms such as steatosis to a serious, life-shortening illness – the liver cirrhosis, can be caused by alcohol consumption. Therapeutic procedures for people with alcoholic liver damages include above all change of lifestyle, abstinence from alcohol consumption and nutritional and pharmacological therapy. Liver transplant surgery is required in serious cases.
The main aim of this communication is to find out how the liver transplant influences quality of patients’ everyday lives improves after liver transplant. We have divided this aim in several questions: do the patients’ attitudes towards use of alcohol change in relation to the subsequent outpatient treatments? Is it possible to collect objective markers related to alcohol usage in patients after liver transplant? Are there any interconnections between the patients’ subjective attitude towards alcohol, quality of their lives and objective evidence of their alcohol use?
Data collection method. To this end a structured questionnaire was used based on standardised instruments WHOQOL-BREF and AUDIT.
The research sample. Consisted of 96 patients after liver transplant, who were treated in the Institute for Clinical and Experimental Medicine in Prague.
Data analysis method. The collected data was processed by the method of descriptive statistics and the results presented in individual tables and charts.
Conclusion and results. The results indicate that patients after liver transplant perceive the quality of their lives relatively without regard to their age and sex. The overall number of patients evaluate their quality of life as average, no significant differences between quality of life in men and women have been found. Answers from the AUDIT questionnaire demonstrate that absolute majority of patients experience no problems in relation to alcohol use, as proved also by their laboratory values. The patients who underwent liver transplant can return to their regular pre-transplant lifestyle without serious complications. These people can even get back to their original professions, especially if they are middle-aged and their jobs do not require manually demanding activities.
Keywords:
alcohol – Quality of life – relapse – liver transplantation
Zdroje
1. Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. AUDIT: The Alcohol Use Disorders Identification Test. Guidelines for use in primary care. Second Edition. Geneva: World Health Organization 2001.
2. Bravata DM, Olkin I, Barnato AE, et al. Health-related quality of life after liver transplantation: a meta-analysis. Liver Transpl Surg 1999; 5(4): 318–331.
3. Dragomerická E. Česká verze dotazníku kvality života WHOQOL. Překlad položek a konstrukce škál. Psychiatrie 2006; 10(2): 68–73.
4. Dudley T, Chaplin D, Clifford C, Mutimer DJ. Quality of life after liver transplantation for hepatitis C infection. Qual Life Res 2007; 16(8): 1299–1308.
5. Ehrmann J. Alkohol a játra. Praha: Grada Publishing 2006.
6. Hepp J, Zapata R, Buckel E, et al. General considerations, indications and contraindications for liver transplantation in Chile. Rev Med Chil 2008; 136(6): 793–804.
7. Heřmanová E. Koncepty, teorie a měření kvality života. Praha: Sociologické nakladatelství 2012.
8. Klener P, a kol. Vnitřní lékařství, díl 3. B. Choroby jater. Praha: Karolinum 1997.
9. Liangpunsakul S, Qi R, Crabb DW, Witzmann F. Relationship between alcohol drinking and aspartate aminotransferase:alanine aminotransferase (AST:ALT) ratio, mean corpuscular volume (MCV), gamma-glutamyl transpeptidase (GGT), and apolipoprotein A1 and B in the U.S. population. J Stud Alcohol Drugs 2010; 71(2): 249–252.
10. Payne J, a kol. Kvalita života a zdraví. Praha: Triton 2005.
11. Pfitzmann R, Schwenzer J, Rayes N, et al. Long-term survival and predictors of relapse after orthotopic liver transplantation for alcoholic liver disease. Liver Transpl 2007; 13(2): 197–205.
12. Popov P. Alkohol. In Kalina, K. (Ed.). Drogy a drogové závislosti: Mezioborový přístup 1 (pp. 1512157). Praha: Úřad vlády České republiky 2003.
13. Sherlocková S, Dooley J. Nemoci jater a žlučových cest. Překlad 11. vydání. Hradec Králové: Olga Čermáková 2004.
14. Sobhonsklidsuk A, Silpakit C, Kongsakon R, et al. Factors influencing health-related quality of life in chronic liver disease. World J Gastroenterol 2006; 12(48): 7786–7791.
15. Sumskiene J, Sumskas L, Petrauskas D, Kupcinskas L. Diseasespecific health-related quality of life and its determinants in liver cirrhosis patients in Lithuania. World J Gastroenterol 2006; 12(48): 7792–7797.
16. Trachtová E. Potřeby nemocného v ošetřovatelském procesu. 2. vydání. Brno: Národní centrum ošetřovatelství a nelékařských zdravotnických oborů 2001.
17. Trunečka P. Co je třeba vědět o transplantaci jater. Příručka pro pacienty před a po transplantaci a jejich blízké. Plzeň: Euroverlag 2004.
18. Trunečka P, a kol. Transplantace jater. Praha: Karolinum 2009.
19. Younossi ZM, Boparai N, Price LL, et al. Chronic liver disease and health-related quality of life. Am J Gastroenterol 2001; 96(7): 2199–2205.
20. Zavoral M, Venerová J, a kol. Gastroenterologie a hepatologie. Praha: Triton 2007.
Štítky
General practitioner for children and adolescents General practitioner for adultsČlánok vyšiel v časopise
General Practitioner
2021 Číslo 6
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- Memantine Eases Daily Life for Patients and Caregivers
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
- Spasmolytic Effect of Metamizole
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
Najčítanejšie v tomto čísle
- Quality of life of patients after orthotopic liver transplantation performed for alcoholic cirrhosis
- Can GPs ease the plight of informal carers?
- Specifics of evidence-based practice guidelines for public health domain and proposal of an algorithm for their development and evaluation
- Mesenchymal stem cells business – importance of informed consent