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preLekára.sk / Journals / General Practitioner / 2023 - 6

Oral xenogenic immunomodulating peptide – transfer factor

Česká verzia

Authors: J. Richter 1;  V. Větvička 2
Authors place of work: Zdravotní ústav se sídlem v Ústí nad Labem Centrum imunologie a mikrobiologie Vedoucí: Ing. Eduard Ježo 1;  University of Louisville, KY, USA Department of Pathology and Laboratory Medicine Vedoucí: Eyas M. Hattab, MD, MBA 2
Published in the journal: Prakt. Lék. 2023; 103(6): 304-308
Category: Of different specialties

Summary

Transfer factor (TF) was described in 1955 by S. Lawrence. In 1976, as part of a WHO scholarship, contact was made with C.H. Kirkpatrick, who provided us with the preparation methodology. Kirkpatrick in 1992 characterized the specific transfer factor at the molecular level. Thanks to him, in 1967, at our workplace, xenogenic transfer factor from pig bloodwas prepared in the application form of oral administration. The transfer factor was gradually introduced as part of theresearch not only in clinical practice, but also in preventive application in individuals with a significant burden on theimmune system due to various factors, including physical stress, post-infection insufficiency of the immune system or inpatients after radiation and chemotherapy treatment of cancer. We verified new approaches to the definition of TF andbroadening the spectrum of induction of post-application changes in a group of elite athletes, hockey representatives,where we confirmed the reported changes in immunoglobulin values, but we also found other significant changes, especially in the spectrum of proteins affecting the metabolism of iron and other minerals. In the last period ofapplication in the post-COVID-19 syndrome, we found a significant benefit of TF application for the rehabilitation of thepatient and his problems, where the possibility of applying the specific component of the SARS Co V-2 virus, which infects pig farms, can be assumed. The findings point to the necessity of further monitoring of the issue of TF, which could be beneficial for a detailed definition of this food supplement.

Keywords:

prevention – xenogenic transfer factor – oral application – clinic

Zdroje
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adresa pro korespondenci:
MUDr. Josef Richter, CSc.
Zdravotní ústav se sídlem v Ústí nad Labem
Centrum imunologie a mikrobiologie
Na Kabátě 229, 400 11 Ústí nad Labem
e-mail: imuno.alergo@zuusti.cz

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General Practitioner

Číslo 6
2023 Číslo 6
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