Cause of clinical manifestations of chronic venous insufficiency in patients with overweight and obesity

Česká verzia

Authors: D. Musil ¹; J. Herman ²
Authors place of work: Nestátní interní a cévní ambulance, II. poliklinika, Olomouc ¹; II. chirurgická klinika Lékařské fakulty UP a FN Olomouc, přednosta prof. MUDr. Miloslav Duda, DrSc. ²
Published in the journal: Vnitř Lék 2005; 51(5): 523-528
Category: Original Contributions

Summary

The aim of the paper was to answer the question to what degree clinical manifestations of chronic venous insufficiency in patients with overweight and obesity have connection with increased body weight, possibly with its various complications, and to what degree they are based on underlying primary infliction of lower limb venous system. Population consisted of 100 patients ((78 females a 22 males) with manifestations of chronic venous insufficiency (C1–C6 according to CEAP). Nutrition status of the patients was evaluated based on BMI: control group with BMI ≥ 20–25 kg/m² (n = 49), monitored group with BMI ≥ 26 kg/m² (n = 43) was divided in overweight patients (BMI ≥ 26–29 kg/m²) and obese patients (BMI ≥ 30 kg/m²). In control group of patients with BMI ≥ 20–25 kg/m² we demonstrated primary infliction of venous wall (67.3%) as a main cause of clinical manifestations of chronic venous insufficiency, which was exhibited by reflux in superficial venous system and supported by positive family history (77.6%) and high correlation between positive family history and the infliction of superficial veins (67.3%). In monitored group with BMI ≥ 26 kg/m² and BMI ≥ 30 kg/m²) causes of clinical manifestations of chronic venous insufficiency can be divided at least into three groups: 1. primary infliction of venous wall (55% verweight patients, 20.8% obese patients) supported by positive family history, 2. obesity as a primary cause of symptoms of chronic venous insufficiency, 3. obesity as a main risk factor of various diseases which can lead to secondary posttraumatic or postthrombotic infliction of lower limb venous system.

Key words:
chronic venous insufficiency – duplex sonography – risk factors – overweight – obesity – BMI – heredity – reflux

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