Goblet cell carcinoid of the appendix

Česká verzia

Authors: O. Louthan
Authors place of work: Ambulance pro neuroendokrinní nádory IV. interní kliniky 1. lékařské fakulty UK a VFN Praha, přednosta prof. MU Dr. Aleš Žák, DrSc.
Published in the journal: Vnitř Lék 2009; 55(11): 1056-1059
Category: Reviews

Summary

Appendiceal goblet cell carcinoids are mixed tumors including neuroendocrine cells and intestinal type of goblet cells. Compared to typical carcinoids, goblet cell carcinoids are malignant tumors with degree of malignity differing from case to case. Carcinoid syndrom is not present. There is poor prognosis in larger tumors. Appendectomy is a sufficient therapeutical approach in small tumors, hemicolectomy should be performed in larger ones. There is limited experience with chemotherapy in metastasizing tumors and sporadic with somatostatin analogues.

Key words:
appendectomy – goblet cell carcinoid – chemotherapy – somatostatin receptor scintigraphy – somatostatin analogues

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