Bioelectrical impedance analysis for comparison of the body composition in type 1 diabetes patients, obese patients and healthy volunteers

Česká verzia

Authors: L. Baxová; M. Žourek; V. Frantová; K. Kovářová; Z. Rušavý
Authors place of work: Diabetologické centrum I. interní kliniky Lékařské fakulty UK a FN Plzeň, přednosta doc. MUDr. Martin Matějovič, Ph. D.
Published in the journal: Vnitř Lék 2009; 55(5): 462-467
Category: Original Contributions

Summary

Background:
Effects of glycaemic control and insulin treatment on body composition in type 1 diabetes patients have not been clearly proven yet.

Aim:
Comparison of the body composition in type 1 diabetes patients, obese patients and healthy volunteers using multifrequency bioelectrical impedance analysis.

Methods:
Multifrequency bioelectrical impedance measurements were performed on 153 type 1 diabetes patients, 176 obese patients and on 159 healthy controls of the same age and gender. HbA_1c level, duration of disease and daily dose of insulin were measured in diabetes patients.

Results:
Significant differences were observed in body composition between obese patients and both type 1 diabetes patients and healthy controls. Higher fat mass (FM) and body cell mass (BCM) and lower lean body mass (LBM) were observed in obese patients. Only a higher reactance by the healthy controls (56.75 Ω ± 11.22 vs 53.27 Ω ± 7.97, p < 0.05) was observed between type 1 diabetes patients and healthy controls. No significant differences were observed in other parameters of body composition between these two groups. HbA_1c level negatively correlated with LBM in the diabetes patients. The duration of disease negatively correlated with BCM. And a negative correlation was also found between daily dose of insulin (IU/kg) and weight and LBM.

Conclusions:
The treated type 1 diabetes does not influence the body composition. We found a negative correlation between HbA_1c level and LBM, between duration of disease and BCM and between daily dose of insulin and weight and LBM. Higher FM and BCM was observed in obese patients, lower LBM is due to the abnormally high level in diabetes patients and healthy controls.

Key words:
body composition – bioelectrical impedance analysis – type 1 diabetes – obesity – insulin – HbA_1c

Zdroje

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