Turner’s syndrome requires multidisciplinary approach

Česká verzia

Authors: M. Berková ¹; Z. Berka ²; Z. Krčová ³
Authors place of work: I. interní klinika Lékařské fakulty UP a FN Olomouc, přednosta prof. MUDr. Jan Lukl, CSc. ¹; II. interní klinika Lékařské fakulty UP a FN Olomouc, přednosta doc. MUDr. Vlastimil Procházka, Ph. D. ²; Ústav patologie Lékařské fakulty UP a FN Olomouc, přednosta doc. MUDr. Martin Tichý, CSc. ³
Published in the journal: Vnitř Lék 2009; 55(5): 501-505
Category: Reviews

Summary

Turner syndrome is one of the most frequent genetic disorders, the result of complete or partial monosomy of the X chromosome. It affects 1 : 2,500 live female births. The principal features of Turner syndrome are short stature and ovarian dysgenesis accompanied by estrogen deficit. Turner syndrome is associated with further numerous, more or less serious abnormalities and high risk of cardiovascular mortality. The article concisely summarizes the most frequent problems in Turner syndrome and emphasizes the need of multidisciplinary care for affected patients.

Key words:
Turner syndrome – ovarian dysgenesis – estrogen deficit – congenital disease – cardiovascular mortality

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