Polycystic ovary syndrome and autoimmune diseases

Česká verzia

Authors: J. Petríková; I. Lazúrová
Authors place of work: I. interná klinika Lekárskej fakulty UPJŠ a FN L. Pasteura Košice, Slovenská republika, prednostka prof. MU Dr. Ivica Lazúrová, CSc.
Published in the journal: Vnitř Lék 2010; 56(5): 414-417
Category: Reviews

Summary

Polycystic ovary syndrome (PCOS) is characterized by laboratory or clinical signs of hyperandrogenism with chronic anovulation and is currently one of the most frequent endocrinopaties in women of fertile age. Syndrome is associated with a variety of endocrine and metabolic disturbances and according to results of scientific work could be possibly associated with some autoimmune diseases. It seems that the prevalence of autoimmune tyroiditis is important among these patients. Recent studies reveal higher incidence of organ – non specific autoantibodies, but their clinical significance is unknown to date. Further studies are required to determine the role of organ specific and non‑specific autoantibodies in patients with PCOS. According to determine an etiology of the syndrome one of the possible outcomes could be investigation of anti‑follicular antibody.

Key words:
PCOS – autoimmunity – etiology – autoantibodies

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