Endocarditis 2007: Results of a multicentric study on occurence and characteristics of infective endocarditis

Česká verzia

Authors: J. Beneš; R. Baloun; O. Džupová
Authors place of work: Klinika infekčních nemocí 3. lékařské fakulty UK a FN Na Bulovce Praha, přednosta doc. MUDr. Jiří Beneš, CSc. a skupina hlásících lékařů Romana Balková (Nemocnice s poliklinikou Česká Lípa, a. s. ), Marián Branný (Nemocnice Třinec – Podlesí, s. r. o. )
Published in the journal: Vnitř Lék 2011; 57(2): 147-154
Category: Original Contributions

Summary

Aim:
To recognize incidence and epidemiological characteristics of infective endocarditis (IE) in the Czech Republic.

Methods:
A prospective multicentre observational study on occurence and characteristics of IE in 29 hospitals within one year. A cooperative physician in every hospital reported all cases of IE that occured in pre-defined hospital attraction area in 12 consecutive months. A unified anonymous form was used for reporting. Only patients fulfilling the modified Duke criteria were enrolled.

Results:
One hundred and thirty-four cases of IE were reported. Thus, crude incidence of IE appeared 3.4 cases/100,000/year. Vegetations were found on aortic valves in 45.5% and on mitral valves in 40.3%. The most common etiological agent was Staphylococcus aureus (29.9%). Etiology was not established in 45 cases (33.6%), mostly due to previous antibiotic treatment. The most frequent predisposing conditions were purulent infections, namely in lower extremities, and previous invasive cardiac procedures (cardiac surgery, permanent pacemaker/defibrillator etc.). Heart surgery within antibiotic treatment was performed in 36 patients (26.9%). Overall mortality was also 26.9%. Mortality was significantly higher in hospitals that did not dispose of transesophageal echocardiography (TEE).

Conclusion:
We assume the real incidence of IE was slightly higher than we had found. The possible causes of such discreapance are discussed.

Key words:
infective endocarditis – incidence – predisposing conditions – echocardiography

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