Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form

Česká verzia

Authors: J. Václavík
Authors place of work: I. interní klinika – kardiologická Lékařské fakulty UP a FN Olomouc, přednosta doc. MU Dr. Miloš Táborský, CSc., FESC, MBA
Published in the journal: Vnitř Lék 2013; 59(4): 290-294
Category: Review

Summary

Perindopril is a long acting ACE inhibitor with a 24- hour lasting effect. Its positive effect on a reduction in cardiovascular events has been confirmed in a range of large randomized clinical trials and in a wide spectrum of patients: hypertonic patients, diabetics, patients with stable ischaemic heart disease, elderly patients, or patients who have undergone a cerebrovascular accident. The extending range of various fixed combinations as well as new pharmaceutical dosage forms, including the newly introduced orodispersible tablets of perindopril, enables optimization of treatment for every patient, an increase in the patient‘s treatment adherence, and also improvement in long‑term blood pressure control with a consequent effect on reduction of morbidity and mortality.

Key words:
hypertension – cardiovascular disease – treatment – perindopril – pharmaceutical dosage forms – orodispersible tablets

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