Calcium, vitamin D and health

Česká verzia

Authors: Jaroslav Blahoš ¹; Václav Vyskočil ²
Authors place of work: Osteocentrum Interní kliniky 1. LF UK a ÚVN Praha, přednosta prof. MUDr. Miroslav Zavoral, Ph. D. ¹; Osteocentrum – oddělení klinické osteologie II. interní kliniky LF UK a FN Plzeň, přednosta prof. MUDr. Jan Filipovský, CSc. ²
Published in the journal: Vnitř Lék 2014; 60(9): 691-695
Category:

Summary

The authors describe briefly recent views on physiological, pathological and practical aspects of calcium and vitamin D. The sources of calcium are the nutrients, mammal milk and milk products as well as pharmaceutical products. Their beneficial and potentially hazardous effects are discussed. The insufficiency of vitamin D [25(OH)D₃] is a global health problem and the necessity of monitoring of this hepatic metabolite (as a marker) is emphasized due to its role in physiological and pathological processes.

Key words:
calcium – physiological and pathophysiological effects – vitamin D

Zdroje

1. Blahoš J, Zamrazil V. Endokrinologie, interdisciplinární obor. Triton: Praha 2006: 103–119. ISBN 80–7254–788–7.

2. Joo NS, Dawson-Hughes B, Kim YS et al. Impact of calcium and vitamin D insufficiencies on serum parathyroid hormone and bone mineral density: analysis of the fourth and fifth Korea National Health and Nutrition Examination Survey (KNHANES IV-3, 2009 and KNHANES V-1, 2010). J Bone Miner Res 2013; 28(4): 764–770.

3. Blahos J, Care AD, Sommerville A. The effect of betamethasone on duodenal calcium absorption and 1,25-dihydroxy vitamin D production in the chick. Horm Metab Res 1983; 15(4): 197–200.

4. Blahos J. Treatment and prevention of osteoporosis. Wien Med Wochenschr 2007; 157(23–24): 589–592.

5. Mithal A, Wahl DA, Bonjour JP et al. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 2009; 20(11): 1807–1820.

6. Reid IR, Bolland MJ, Avenell A et al. Cardiovascular effects on calcium supplementation. Osteoporos Int 2011; 22(6): 1649–1658.

7. Paik JM, Curhan GC, Sun Q. Calcium suplement intake and risk of cardiovascular disease in women. Osteoporos Int 2014; 25(8): 2047–2056.

8. Wacławski-Wende J, Kotchen JM, Anderson GL et al. Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med 2006; 354(7): 684–694.

9. Blahoš J. Diabetes mellitus a kost. In: Kvapil M (ed.) Diabetologie 2011. Triton: Praha 2011: 197–201. ISBN 978–80–7387–461–2.

10. Pramyothin P, Holick MF. Vitamin D supplementation: guidelines and evidence for subclinical deficiency. Curr Opin Gastroenterol 2012; 28(2): 139–150.

11. Kamphuis LS, Bonte-Mineur F, van Laar JA et al. Calcium and vitamin D in sarcoidosis: is supplementation safe? J Bone Miner Res 2014. Dostupné z DOI: <http://doi: 10.1002/jbmr.2262>.