Novel diagnostic and therapeutic procedures in diabetic nephropathy

Česká verzia

Authors: Peter Ponťuch
Authors place of work: IV. interná klinika LF UK a UN Bratislava, Slovenská republika, prednosta prof. MUDr. Peter Ponťuch, CSc.
Published in the journal: Vnitř Lék 2015; 61(Suppl 5): 57-62
Category: Reviews

Summary

Epidemiological studies show increasing prevalence of diabetic nephropathy. Diabetic patients with chronic kidney disease are the biggest group from among patients on renal replacement therapy. Renal Pathology Society developed pathological classification of diabetic nephropathy. The cardinal biochemical diagnostic parameters are albuminuria and estimated glomerular filtration rate. European Renal Best Practice work group developed Clinical Practice Guideline on management of patients with diabetes and chronic kidney disease stage 3b or higher.

Key words:
epidemiology of diabetic nephropathy – diagnostics of diabetic nephropathy – therapy of chronic kidney disease in diabetic patients

Zdroje

1. de Boer IH, Rue TC, Cleary PA et al. Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: Analysis of Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Cohort. Arch Intern Med 2011; 171(5): 412–420.

2. Titze S, Schmid M, Köttgen A et al. Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort. Nephrol Dial Transplant 2015; 30(3): 441–451.

3. Martinka E, Ponťuch P. The prevalence of diabetic nephropathy in patients with type 2 diabetes mellitus in Slovakia. The Nefriti Study. In: 51st meeting of European Association for the Study of Diabetes. Stockholm 2015. A1117.

4. KDIGO CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013; 3(1): 1–150. Dostupné z WWW: <http://www.kdigo.org/clinical_practice_guidelines/pdf/CKD/KDIGO_2012_CKD_GL.pdf>.

5. Inker LA, Levey AS. Estimating GFR using the chronic kidney disease epidemiology collaboration (CKD-EPI) 2009 creatinine equation: the time for change is now. Nephrol Dial Transplant 2013; 28(6): 1390–1396.

6. Hallan SI, Gansevoort RT. Moderator´s view: Estimating glomerular filtration rate – the past, present and future. Nephrol Dial Transplant 2013; 28(6): 1404–1406.

7. Tervaert TW, Mooyaart AL, Amann K et al. Pathologic classification of diabetic nephropathy. J Am Soc Nephrol 2010; 21(4): 556–563.

8. Mise K, Hoshino J, Ubara Y et al. Renal prognosis a long time after renal biopsy on patients with diabetic nephropathy. Nephrol Dial Transplant 2014; 29(1): 109–118.

9. An Y, Xu F, Le W et al. Renal histologic changes and the outcome in patients with diabetic nephropathy. Nephrol Dial Transplant 2015; 30(2): 257–266.

10. American Diabetes Association. Standards of medical care in diabetes-2015. Diabetes Care 2015; 38(Suppl 1): S4.

11. KDIGO work group. KDIGO 2012 clinical practice guideline for the management of blood pressure in chronic kidney disease. Kidney Int Suppl 2012; 2(5): 1–85.

12. Clinical practice guidelines on management of patients with diabetes and chronic kidney disease stage 3b or higher (eGFR<45 ml/min). Nephrol Dial Transplant 2015; 30: ii1-ii142. Dostupné z DOI: <http://dx.doi.org/10.1093/ndt/gfv100>.

13. Datta N, Miura N, Saleem M et al. Overexpression of transcription factor FOXC2 induces dedifferentiation and increased motility of cultured human podocytes. In: 28th European Diabetic Nephropathy Study Group meeting, Gentofte 2015: 12 (Abstract).

14. Oram R, Olateju T, Ling Y et al. 5-year renal outcomes after islet transplantation in 111 subjects with and without CKD/DN. In: 28th European Diabetic Nephropathy Study Group meeting. Gentofte 2015:19 (Abstract).