Type 2 diabetes mellitus and chronic kidney disease
Authors:
Peter Ponťuch
Authors place of work:
IV. interná klinika LF UK a UNB, Nemocnica sv. Cyrila a Metoda, Bratislava, Slovenská republika
Published in the journal:
Vnitř Lék 2017; 63(3): 188-192
Category:
Reviews
Summary
The number of type 2 diabetic patients is increasing world-wide and a prediction of prevalence of chronic kidney disease up to 2025 in European diabetic population is alarming. Albuminuria and estimated glomerular filtration rate are cardinal biochemical parameters in diagnostics of diabetic nephropathy. Following diagnostic methods are also used: renal ultrasonography, ophthalmoscopy and in not clarified cases renal biopsy. Long-term optimal glycemic control, efficient antihypertensive treatment by angiotensin converting enzyme inhibitor, or angiotensin receptor blocker and recommended protein intake is a cornerstone of therapy. The research is presently focused on new pathophysiological mechanisms, as analysis of genome, microRNA, kidney injury biomarkers and proteomes.
Key words:
chronic kidney disease – type 2 diabetes mellitus
Zdroje
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Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Internal Medicine
2017 Číslo 3
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