#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Current view of treatment of hypoglycemia


Authors: Jan Brož 1;  Jana Urbanová 2;  Marisa Nunes 1;  Martina Tuháčková 1;  Ludmila Brunerová 2;  Denisa Janíčková Žďárská 1
Authors place of work: Interní klinika 2. LF UK a FN Motol, Praha 1;  Centrum pro výzkum diabetu, metabolismu a výživy, II. interní klinika 3. LF UK a FN Královské Vinohrady, Praha 2
Published in the journal: Vnitř Lék 2019; 65(4): 295-299
Category:

Summary

Hypoglycemia is a side effect of the therapy primarily with insulin, sulphonylurea derivates and glinides. Its therapy is based on the immediate ingestion of sacharides, preferably glucose. Amount of 15–20 g is recommended as its optimal dose, although several recent studies are suggesting amount related to the patient´s weight. The therapy of severe hypoglycemia in the non-professional settings is based on glucagon injection, in the professional ones intravenous administration of glucose is preferable option.

 

Keywords:

hypoglycemia – therapy – type 2 diabetes


Zdroje
  1. McCoy RG, Van Houten HK et al. Increased mortality of patients with diabetes reporting severe hypoglycemia. Diabetes Care 2012; 35(9): 1897–1901. Dostupné z DOI: <http://dx.doi.org/10.2337/dc11–2054>.
  2. Hemmingsen B, Lund SS, Gluud C et al. Intensive glycaemic control for patients with type 2 diabetes: systematic review with meta-analysis and trial sequential analysis of randomised clinical trials. BMJ 2011; 343: d6898. Dostupné z DOI: <http://dx.doi.org/10.1136/bmj.d6898>.
  3. Bolek T, Samoš M, Mokáň M et al. Akútne príčiny náhlych úmrtí u pacientov so závažnou hypoglykémiou. Vnitř Lék 2016; 62(6): 462–466.
  4. [International Hypoglycemia Study Group]. Minimizing Hypoglycemia in Diabetes. Diabetes Care 2015; 38(8): 1583–1591. Dostupné z DOI: <http://dx.doi.org/10.2337/dc15–0279>.
  5. American Diabetes Association. Glycemic targets. Sec. 6. In Standards of Medical Care in Diabetes – 2018. Diabetes Care 2018; 41(Suppl 1): S55-S64. Dostupné z DOI: <http://dx.doi.org/https://doi.org/10.2337/dc18-S00>.
  6. Diabetes Canada Clinical Practice Guidelines Expert Committee. Diabetes Canada 2018 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada. Can J Diabetes 2018; 42(Suppl 1): S1-S325. Dostupné z DOI: <https://doi.org/10.1016/j.jcjd.2017.10.005>.
  7. [Joint British Diabetes Societies – Inpatient Care Group (JBDS-IP)]. The Hospital Management of Hypoglycaemia in Adults with Diabetes Mellitus. 3rd ed. Revised April 2018. Dostupné z WWW: <https://abcd.care/joint-british-diabetes-societies-jbds-inpatient-care-group> nebo <www.diabetes.org.uk/joint-british-diabetes-society>.
  8. Brodows RG, Williams C, Amatruda JM. Treatment of insulin reactions in diabetics. JAMA 1984; 252(24): 3378–3381.
  9. Slama G, Traynard PY, Desplanque N et al. The search for an optimized treatment of hypoglycemia. Carbohydrates in tablets, solutin, or gel for the correction of insulin reactions. Arch Intern Med 1990; 150(3): 589–593.
  10. Husband AC, Crawford S, McCoy LA et al. The effectiveness of glucose, sucrose, and fructose in treating hypoglycaemia in children with type 1 diabetes. Pediatr Diabetes 2009; 11(3): 154–158. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1399–5448.2009.00558.x>.
  11. Brodows RG, Williams C, Amatruda JM. Treatment of insulin reactions in diabetics. JAMA 1984; 252(24): 3378–3381.
  12. Wiethop BV, Cryer PE. Alanine and terbutaline in treatment of hypoglycemia in IDDM. Diabetes Care 1993; 16(8): 1131–1136.
  13. Bryden KS, Neil A, Mayou RA et al. Eating habits, bodyweight, and insulin misuse. A longitudinal study of teenagers and young adults with type 1 diabetes. Diabetes Care 1999; 22(12): 1956–1960.
  14. Vindedzis S, Marsh B, Sherriff J et al. Dietary treatment of hypoglycaemia: should the Australian recommendation be increased? Intern Med J2012; 42(7): 830–833. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1445–5994.2012.02831.x>.
  15. McTravish L, Krebs JD, Weatherall M et al. Weight-based hypoglycaemia treatment protocol for adults with Type 1 diabetes: a randomized crossover clinical trial. Diabet Med 2015; 32(9): 1143–1148. Dostupné z DOI: <http://dx.doi.org/10.1111/dme.12730>.
  16. McTavish L, Corley B, Weatherall M et al. Weight-based carbohydrate treatment of hypoglycaemia in people with Type 1 diabetes using insulin pump therapy: a randomized crossover clinical trial. Diabet Med 2018; 35(3): 339–346. Dostupné z DOI: <http://dx.doi.org/10.1111/dme.13576>.
  17. Krebs JD, Weatherall M, Corley B et al. Optimizing the management of hypoglycaemia in individuals with type 2 diabetes: A randomized crossover comparison of a weight-based protocol compared with two fixed-dose glucose regimens. Diabetes Obes Metab 2018; 20(5): 1256–1261. Dostupné z DOI: <http://dx.doi.org/10.1111/dom.13231>.
  18. Yale JF, Dulude H, Egeth M et al. Faster use and fewer failures with needle-free nasal gucagon versus injectable glucagon in severe hypoglycemia rescue: a simulation study. Diabetes Technol Ther 2017; 19(7): 423–432. Dostupné z DOI: <http://dx.doi.org/10.1089/dia.2016.0460>.
  19. Wiethop BV, Cryer PE. Alanine and Terbutaline in Treatment of Hypoglycemia in IDDM. Diabetes Care 1993; 16(8): 1131–1136.
  20. Hall-Boyer K, Zaloga GP, Chernow B. Glucagon: hormone or therapeutic agent? Crit Care Med 1974; 12(7): 584–589.
  21. Lee H, Hosein EA. Chronic alcohol feeding and its withdrawal on the structure and function of the rat liver plasma membrane: a study with 125I-labelled glucagon binding as a metabolic probe. Can J Physiol Pharmacol 1982; 60(9): 1171–1176.
  22. American Medical Association. Division of Drugs and Toxicology. Drug evaluations annual 1994. American Medical Association: Chicago 1993. ISBN 08997060299780899706023.
  23. Škrha J. Hypoglykémie – důležitý fenomén moderní léčby diabetu mellitu. Remedia 2008; 18(Suppl 1): S34-S41.
  24. [Joint British Diabetes Societies – Inpatient Care Group (JBDS-IP)]. The Hospital Management of Hypoglycaemia in Adults with Diabetes Mellitus. 3rd ed. Revised April 2018. Dostupné z WWW: <https://abcd.care/joint-british-diabetes-societies-jbds-inpatient-care-group> nebo <www.diabetes.org.uk/joint-british-diabetes-society>.
  25. Moore C, Woollard M. Dextrose 10% or 50% in the treatment of hypoglycaemia out of hospital? A randomised controlled trial. Emerg Med J 2005; 22(7): 512–515. <http://dx.doi.org/10.1136/emj.2004.020693>.
  26. Kiefer MV, Gene Hern H, Alter HJ et al. Dextrose 10% in the treatment of out-of-hospital hypoglycemia. Prehosp Disaster Med 2014; 29(4): 190–194. <http://dx.doi.org/10.1017/S1049023X14000284>.
  27. Klein-Schwartz W, Stassinos GL, Isbister GK. Treatment of sulfonylurea and insulin overdose. Br J Clin Pharmacol 2016; 81(3): 496–504. Dostupné z DOI: <http://dx.doi.org/10.1111/bcp.12822>.
Štítky
Diabetology Endocrinology Internal medicine

Článok vyšiel v časopise

Internal Medicine

Číslo 4

2019 Číslo 4
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#