Thymoma – disease of many faces

Česká verzia

Authors: Kateřina Pokorná; Vladimír Kojecký
Authors place of work: Interní oddělení, Nemocnice Tomáše Bati ve Zlíně
Published in the journal: Vnitř Lék 2021; 67(4): 240-243
Category: Case reports

Summary

A thymoma belongs to rather rare tumors, although it holds the first place among primary mediastinal tumors in adults. The biological characteristics of thymomas are considerably divergent. The tumors are usually asymptomatic at the begining, later due to a local spread, symptoms from the infiltration or compression of adjacent structures arise, they metastasize rarely. Thymomas are often associated with various autoimmune or endocrinologic diseases. The authors present case of the patient with less common paraneoplasia – autoimmune hemolytic anemia (AIHA). Main strategy of treatment thymom with AIHA isn´t clear. The most important seems to be the early started corticotherapy. Achieving remission of secondary AIHA has importace in following therapy of thymoma – surgical resection or chemotherapy. Thymectomy has positive effect on the course of associated paraneoplastic syndromes and prognosis in general.

Keywords:

autoimunne hemolytic anemia – paraneoplastic symptom – thymoma – warm antibodies

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