Development of recommendations for the use of venoactive drugs in the treatment of chronic venous disease – where they are effective and where they are not

Česká verzia

Authors: Dalibor Musil
Authors place of work: Interní a kardiologická klinika Fakultní nemocnice Ostrava a LF Ostravské univerzity
Published in the journal: Vnitř Lék 2022; 68(4): 234-239
Category: Review Articles

Summary

The article provides an overview of the development of recommendations for indications of venoactive drugs for treating symptoms and signs associated with chronic venous disease (CVD). Venoactive drugs may be beneficial in patients with subjective problems and/or swelling of the lower limbs, after surgery for varicose veins, in chronic venous insufficiency or in microcirculatory disorders. They are not indicated in asymptomatic patients with CVD, in the prevention of varicose veins or to prevent their progression. Drugs with proven efficacy in clinical trials should be preferred.

Keywords:

Randomized controlled trials – venoactive drugs – pentoxifylline – sulodexide – strenght of recommendation – level of evidence – GRADE – symptomatic treatment

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