On human longevity – 1. external influences
Authors:
R. Brdička
Authors place of work:
Ústav hematologie a krevní transfuze a Ústav experimentální medicíny AV ČR, Praha
Published in the journal:
Čas. Lék. čes. 2009; 148: 264-268
Category:
Special Articles
Summary
Human life-span is controlled by many factors, both internal (genomic) and external. In this paper only impact of external conditions is to be discussed. External factors are very variable, sometimes difficult to ascertain, but their control is relatively easier to address than the internal ones. The effect of human activities on human lifespan can be positive or negative. Experimental results have shown that one of the ways leading to prolongation of life-span is caloric restriction (CR). There are, of course, many other factors, not only of nurture character, inflicting on quality and length of human life. Some of them are human products including stress with different levels of inherited ability to resist it, but also possibility to improve individual capacity to control its effect due to hormesis.
Prolongation of life expectancy – ageing of the population has become an economic burden in many countries, especially for social and health services.
Key words:
longevity, ageing, expected life-span, caloric restriction, sex differences, hormesis, Hayflick limit.
Zdroje
1. Sander M, Avlund K, Lauritzen M, Gottlieb T, Halliwell B, Stevnsner T, Wewer U, Bohr VA. Aging-From molecules to populations Mechanisms of Ageing and Development 2008; 129: 614–623.
2. Curran SP, Ruvkun G. Lifespan regulation by evolutionarily conserved genes essental for viability. Plos Genet 2007; 3: e56.
3. de Magalhčes, J.P., Budovsky, A., Lehmann, G., Costa, J., Li, Y., Fraifeld, V., Church, G.M. The Human Ageing Genomic Resources: Online databases and tools for biogerontologists Aging Cell 2009; 8: 65–72. http://genomics.senescence.info/ http://genomics.senescence.info/genes/longevity.html http://genomics.senescence.info/genes/query.php?search
4. Batrinos ML. The length of life and eugeria in classical Greece. Hormones (Athens) 2008; 7: 82–83.
5. Yamori Y, Liu L, Mori M, Sagara M, Murakami S, Nara Y, Mizushima S. Taurine as the nutritional factor for the longevity of the Japanese revealed by a world-wide epidemiological survey. Adv Exp Med Biol 2009; 643: 13–25.
6. Bohafé M, Olivieri F. Genetic polymorhims in long-lived people:Cues for the presence of an insulin/IGF-pathway-dependent network affecting human longevity. Molecular and Cellular Endokrinology 2009; 299: 118–123.
7. Shanley DP, Kirkwood TB. Caloric restriction does not enhance longevity in all species and is unlikely to do so in humans. Biogerontology 2006; 7: 165–168.
8. Miyagi S, Iwama N, Kawabata T, Hasegawa K. Longevity and diet in Okinawa, Japan: the past, present and future. Asia Pac J Public Health 2003; 15 (Suppl): S3–S9.
9. Ginter E. Vegetarian diets, chronic diseases and longevity. Bratisl Lek Listy 2008; 109: 463–466.
10. Shimokawa I, Chiba T, Yamaza H, Komatsu T. Longevity genes: insights from calorie restriction and genetic longevity models. Mol Cells 2008; 26: 427–435.
11. Giani JF, Bonkowski MS, MuĖoz MC, Masternak MM, Turyn D, Bartke A, Dominici FP. Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of calorie restriction. J Gerontol A Biol Sci Med Sci 2008; 63: 788–797.
12. Goertzel B, Pennachin C, de Alvarenga Mudado M, de Souza Coelho L. Identifying the genes and genetic interrelationships underlying the impact of calorie restriction on maximum lifespan: an artificial intelligence-based approach Rejuvenation Res 2008; 11: 735–748.
13. Orallo F. Trans-resveratrol: a magical elixir of eternal youth? Curr Med Chem 2008; 15: 1887–1898.
14. López-Torres M, Barja G. [Calorie restriction, oxidative stress and longevity] ve španělštině. Rev Esp Geriatr Gerontol 2008; 43: 252–260.
15. Swindell WR. Genes regulated by caloric restriction have unique roles within transcriptional networks. Mechanisms of Ageing and Development 2008; 129: 580–592.
16. Chipperfield JG. Everyday physical activity as a predictor of late-life mortality. Gerontologist 2008; 48: 349–357.
17. Landi F, Russo A, Cesari M, Pahor M, Liperoti R, Danese P, Bernabei R, Onder G. Walking one hour or more per day prevented mortality among older persons: Results from ilSIRENTE study. Preventive Medicine 2008; 47: 422–426.
18. Muzumdar R, Allison DB, Huffman DM, Ma X, Atzmon G, Einstein FH, Fishman S, Poduval AD, McVei T, Keith SW, Barzilai N. Visceral adipose tissue modulates mammalian longevity. Aging Cell 2008; 7: 438–440.
19. Wolfe RR, Miller SL, Miller KB. Optimal protein intake in the elderly. Clin Nutr 2008; 27: 675–684.
20. Orallo F. Trans-resveratrol: a magical elixir of eternal youth? Curr Med Chem 2008; 15: 1887–1898.
21. Borrás C, Gambini J, Gómez-Cabrera MC, Sastre J, Pallardó FV, Mann GE, ViĖa J. Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: Involvement of estrogen receptors, ERK1/2, and NFB. FASEB J 2006; 20: E1476–E1481.
22. Tarry-Adkins JL, Chen JH, Smith NS, Jones RH, Cherif H, Ozanne SE. Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets. FASEB J 2009; Jan 6. [Epub ahead of print] PMID: 19126595 [PubMed – as supplied by publisher].
23. Maklakov AA, Simpson SJ, Zajitschek F, Hall MD, Dessmann J, Clissold F, Raubenheimer D, Bonduriansky R, Brooks RC. Sex-specific fitness effects of nutrient intake on reproduction and lifespan. Curr Biol 2008; 18: 1062–1066.
24. Piper MD, Bartke A. Diet and aging. Cell Metab 2008; 8: 99–104.
25. Catalano R, Bruckner T, Smith KR. Ambient temperture predicts sex ratios and male longevity. Proc Nat Acad Sci USA 2008; 105: 2244–2247.
26. Verbrugge LM. Sex differentials in health. Public Health Reports 1982; 97: 417–437.
27. Nakamura E, Miyao K. Sex differences in human biological aging Journals of Gerontology – Series A. Biological Sciences and Medical Sciences 2008; 63: 936–944.
28. ViĖa J, Sastre J, Pallardó FV, Gambini J, Borrás C. Modulation of longevity-associated genes by estrogens or phytoestrogens. Biological Chemistry 2008; 389: 273–277.
29. ViĖa J, Boreáš C, Gambini J, Satyre J, Pallardó FV. Why females live Langer than males? Importace of the upregulation of longevity-associatd genes by oesrogenic compounds. FEBS Letters 2005; 579: 2541–2545.
30. Heinrich M, Prieto JM. Diet and healthy ageing 2100: Will we globalise local knowledge systems? Ageing Research Reviews 2008; 7: 249–274.
31. Zhou F, Di YM, Chan E, Du Y-M, Chow VD-W, Xue CC, Lai X, Duan, W. Clinical pharmacogenetics and potential application in personalized medicine. Current Drug Metabolism 2008; 9: 738–784.
32. Vasto S, Carruba G, Lio D, Colonna-Romano G, Di Bona D, Candore G, Caruso C. Inflammation, ageing and cancer. Mechanisms of Ageing and Development 2009; 130: 40–45.
33. Parsons PA. The ecological stress theory of ageing and hormesis: An energetic evolutionary model. Biogerontology 2007; 8: 233–242.
34. Vitetta L, Anton B, Cortizo E, Sali A. Mind-body medicicne: Stress and its impact onoverall health and longevity. Ann NY Acad Sci 2005: 1057: 492–505.
35. Simmonds NJ, Cullinan P, Hodson ME. Growing old with cystic fibrosis – The characteristics of long-term survivors of cystic fibrosis. Respiratory Medicine 2009; 103: 629–635.
36. Blumenthal D, Hsiao W. Privatization and its discontents – The evolving chinese health care system. N Engl J Med 2005; 353: 1165–1170.
37. Gu D, Zhang Z., Zeng Y. Access to healthcare services makes a difference in healthy longevity among older Chinese adults. Social Science and Medicine 2009; 68: 210–219.
38. Benítez-Silva H, Ni H. Health status and health dynamics in an empirical model of expected longevity. Journal of Health Economics 2008; 27: 564–584.
39. Andersen TM. Increasing longevity and social security reforms-A legislative procedure approach. Journal of Public Economics 2008; 92: 633–646.
40. Bogojevic,, A, Balaž A, Karapandža R. Consequences of increased longevity for wealth, fertility, and population growth. Physica A: Statistical Mechanics and its Applications 2008; 387: 543–550.
41. Nabetani A, Ishikawa F. Unusual telomeric DNAs in human telomerase-negative immortalized cells. Molecular and Cellular Biology 2009; 29: 703–713.
42. Jones DL. Aging and the germ line: where mortality and immortality meet. Stem Cell Rev 2007; 3: 192–200.
43. Kirkwood TBL. A systematic look at an old problem. Nature 2008; 451: 644–647.
44. Dwyer J. Starting down the right path: nutrition connections with chronic diseases of later life. Am J Clin Nutr 2006; 83: 415S–420S.
Štítky
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistČlánok vyšiel v časopise
Journal of Czech Physicians
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- Spasmolytic Effect of Metamizole
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
- Metamizole in perioperative treatment in children under 14 years – results of a questionnaire survey from practice
Najčítanejšie v tomto čísle
- Desident CaviCide a new disinfectant
- Child abuse in common family population – a longitudinal study
- From ethicotherapy to modern psychiatry
- On human longevity – 1. external influences