Cardiovascular abnormalities in liver cirrhosis
Authors:
Jana Šmalcová; Radan Brůha
Authors place of work:
IV. interní klinika 1. LF UK a VFN, Praha
Published in the journal:
Čas. Lék. čes. 2013; 152: 123-128
Category:
Review Article
Summary
Cirrhosis of the liver is associated with a number of cardiovascular abnormalities. Characteristic features in cirrhotic patients include hyperdynamic splanchnic as well as systemic circulation. This is related to arterial vasodilation leading to central hypovolaemia, sodium retention and increased intravascular volume. As a result of these changes, signs of systolic and diastolic dysfunction of the heart with electrophysiological correlates can develop; this condition is referred to as cirrhotic cardiomyopathy. Since early diagnosis may be difficult, undiscovered cardiovascular changes can manifest in cardiac failure. It can negatively affect morbidity and mortality of what is already a serious condition such as cirrhosis, and what is a good enough reason for continued research.
Keywords:
cardiomyopathy – hyperdynamic circulation – cirrhosis of the liver – electrophysiological abnormalities – cardiac failure
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