Health effects of ambient ultrafine particles – the project UFIREG
Authors:
Miroslav Dostál 1; Anna Pastorková 1; Stefanie Lanzinger 2; Alexandra Schneider 2; Susanne Bastian 3; Monika Senghaas 4; Ziva Erzen 5; Jiří Novák 6; Teťana Kolodnitska 7; Radim J. Šrám 1; Annette Peters 2
Authors place of work:
Ústav experimentální medicíny AV ČR, Praha
1; Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Deutschland
2; Saxon State Office for Environment, Agriculture and Geology, State Department for Environmental and Agricultural Operations in Saxony, Dresden, Deutschland
3; Research Association Public Health Saxony and Saxony-Anhalt, Faculty of Medicine Carl Gustav Carus, Technical University Dresden, Dresden, Deutschland
4; The National Laboratory of Health, Environment and Food, Celje, Slovenia
5; Český hydrometeorologický ústav, Praha
6; L. I. Medved‘s research center of preventive toxicology, food and chemical safety, Ministry of health, Chernivtsi, Ukraine (State enterprise)
7
Published in the journal:
Čas. Lék. čes. 2015; 154: 176-180
Category:
Original Article
Summary
Background.
The project “Ultrafine particles – an evidence based contribution to the development of regional and European environmental and health policy” (UFIREG) started in July 2011 and ended in December 2014. It was implemented through the Central Europe Programme and co-financed by the European Regional Development Fund. Five cities in four Central European countries participated in the study: Augsburg (Germany), Chernivtsi (Ukraine), Dresden (Germany), Ljubljana (Slovenia) and Prague (Czech Republic). The aim of the UFIREG project was to improve the knowledge base on possible health effects of ambient ultrafine particles (UFP) and to raise overall awareness of environmental and health care authorities and the population.
Methods.
Epidemiological studies in the frame of the UFIREG project have assessed the short-term effects of UFP on human mortality and morbidity, especially in relation to cardiovascular and respiratory diseases. Official statistics were used to determine the association between air pollution concentration and daily (cause-specific: respiratory and cardiovascular) hospital admissions and mortality. Associations of UFP levels and health effects were analysed for each city by use of Poisson regression models adjusting for a number of confounding factors.
Results.
Results on morbidity and mortality effects of UFP were heterogeneous across the five European cities investigated. Overall, an increase in respiratory hospital admissions and mortality could be detected for increases in UFP concentrations. Results on cardiovascular health were less conclusive.
Conclusion.
Further multi-centre studies such as UFIREG are needed preferably investigating several years in order to produce powerful results.
Keywords:
air pollution – ultrafine particles – cardiovascular – respiratory – hospital admissions – mortality
Zdroje
1.WHO. Newsletter WHO Collaborating Centre for Air Quality Management and Air Pollution Control, No, 53, June 2014.
2. WMA. WMA Statement on the prevention of air pollution due to vehicle emissions. The 65th World Medical Assembly, Durban, South Africa, October 2014. http://www.isde.org/activities.html.
3. HEI. HEI Perspectives 3, Understanding the health effects of Ambient Ultrafine particles, Health Effects Institute, Boston, Massachusetts, January 2013, 108 s.
4. Peters A, Veronesi B, Calderon-Garciduenas L, Gehr P, Chen LC, Geiser M, et al. Translocation and potential neurological effects of fine and ultrafine particles a critical update. Part Fibre Toxicol 2006; 3: 13.
5. Novák J, Šilhavý J, Ždímal V, Ondráček J, Zíková N, Dostál M, Pastorková A. Projekt UFIREG – Central Europe. Měření ultrajemných částic a analýza dopadu expozice na lidské zdraví. Ochrana ovzduší 2012; 6: 31–34
6. Ždímal V, Janáč M, Slezáčková Zíková N. Čarodějnice kouří jako fabrika. Vesmír 2014; http://vesmir.cz/2014/05/06/carodejnice-kouri-fabrika/
7. Wichman HE, Spix C,Tuch T, Wölke G, Peters A, Heinrich J, Kreyling WG, Heyder J. Daily mortality and fine and ultrafine particles in Erfurt, Germany part I: role of particle number and particle mass, Res Rep Health Eff Inst 2000; 98: 5–86.
8. Stölzel M, Breitner S, Cyrys J, Pitz M, Wölke G, Peters A, Heinrich J, Kreyling WG, Heyder J. Daily mortality and particulate matter in different size classes in Erfurt, Germany, J Expo Sci Environ Epidemiol 2007; 17(5): 458–467.
9. Andersen ZJ, Olsen TS, Andersen KK, Loft S, Ketzel M, Raaschouelsen O. Association between short-term exposure to ultrafine particles and hospital admissions for stroke in Copenhagen, Denmark, Eur Hart J 2010; 16: 2034–2040.
10. Franck U, Odeh S, Wiedensohler A, Wehner B, Herbath O. The effect of particle size on cardiovascular disorders--the smaller the worse, Sci Total Environ 2011; 409(20): 4217–4221.
11. Braniš M, Vyškovská J, Malý M, Hovorka J. Association of size-resolved number concentrations of particulate matter with cardiovascular and respiratory hospital admissions and mortality in Prague, Czech Republic, Inhal Toxicol 2010; 22(Suppl 2): 21–28.
12. Calderon-Garciduenas L, Maronpot RR, Torres-Jardon R, Henriquez-Roldan C, Schoonhoven R, Acuna-Ayala H, et al. DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration, Toxicol Pathol 2003; 31: 524–538.
13. Cyrys J. Importance of UFP measurements. www.ufireg-central.eu
Štítky
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistČlánok vyšiel v časopise
Journal of Czech Physicians
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- Metamizole vs. Tramadol in Postoperative Analgesia
- Spasmolytic Effect of Metamizole
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
Najčítanejšie v tomto čísle
- Gastric lavage after peroral intoxication – controversial views
- The story of Appendix
- A short history of infectious diseases since the fifties of the last century and the importance of vaccination
- IgA Nephropathy. Facts, uncertainties, and potential causal therapy approaches