Indications to liver transplantation
Authors:
Pavel Taimr
Authors place of work:
Klinika hepatogastroenterologie IKEM, Praha
Published in the journal:
Čas. Lék. čes. 2017; 156: 355-360
Category:
Review Articles
Summary
Liver transplantation should be considered in patients with end-stage liver disease in whom this operation would extend life expectancy beyond what the natural history of underlying disease would predict or in whom transplantation is likely to substantially improve the quality of life.
Liver transplantation is indicated in end-stage liver disease, in selected liver tumors and in fulminant liver failure. The most common indication in adult to transplantation is decompensated liver cirrhosis with life expectancy one year or less. Evaluation and referral to transplantation center should be considered when a major complication of liver cirrhosis occurs – ascites, bleeding due to portal hypertension, hepatorenal syndrome or hepatic encephalopathy. MELD score ≥ 15 is recommended to list patients with end-stage liver disease.
In recent years the indication of decompensated cirrhosis B and C is declining, on contrary, there is an increase in indication for hepatocellular carcinoma and NASH. An extension of indications has been observed recently – patients above 70 years of age, patients with neuroendocrine tumors among others.
In 2016 in Czech Republic total 179 livers were transplanted, but only a small fraction of potential candidates was referred to transplant centers.
Keywords:
liver transplantation, liver cirrhosis, hepatocellular carcinoma, fulminant liver failure
Zdroje
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Štítky
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistČlánok vyšiel v časopise
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Najčítanejšie v tomto čísle
- Indications to liver transplantation
- Intestinal transplantation in Czech Republic
- Organ transplantation from donors after circulatory death
- Psychological problems of patients who survived cardiac arrest out of hospital