Risk factors for postoperative pneumonia in patients after lung resection for non-small cell lung cancer – results of a cohort study
Authors:
Markéta Kepičová 1; Lubomír Tulinský 1; Adéla Kondé 2,3; Čestmír Neoral 1; Lubomír Martínek 1
Authors place of work:
Chirurgická klinika LF OU a FN Ostrava
1; Katedra aplikované matematiky, FEI VŠB-TU Ostrava
2; Útvar náměstka ředitele pro vědu, výzkum a výuku, FN Ostrava
3
Published in the journal:
Čas. Lék. čes. 2024; 163: 94-97
Category:
Original Article
Summary
Postoperative pneumonia is the most common complication in patients after lung resection for non-small cell lung cancer (NSCLC). The tolerable incidence of this complication ranges from 5 to 8 %. The aim of this study was to evaluate the influence of initial risk factors on the incidence of postoperative pneumonia in patients undergoing lung resection for NSCLC.
A retrospective cohort study was conducted at the University Hospital Ostrava between January 1, 2016, and December 31, 2022. All adult patients who underwent pulmonary lobectomy for primary NSCLC during the study period were included in the study.
A total of 350 patients were included in the study. The incidence of postoperative pneumonia was 10.9%. Analysis of baseline risk factors did not show a statistically significant association with the incidence of this complication. The only statistically significant finding was a longer hospital stay in patients with postoperative pneumonia.
The risk of postoperative pneumonia in patients undergoing lung resection for non-small cell lung cancer cannot be clearly explained by the initial risk factors examined alone. The complex nature of this risk also requires a comprehensive approach to prevention, including both patient-centred measures and improved postoperative care.
Keywords:
non-small cell lung carcinoma, postoperative pneumonia, lung resection, risk factors, incidence
Zdroje
- Hoy H, Lynch T, Beck M. Surgical treatment of lung cancer. Crit Care Nurs Clin North Am 2019; 31: 303–313.
- Manerikar A, Querrey M, Cerier E et al. Comparative effectiveness of surgical approaches for lung cancer. J Surg Res 2021; 263: 274–284.
- Bendixen M, Jørgensen OD, Kronborg C et al. Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: a randomised controlled trial. Lancet Oncol 2016; 17: 836–844.
- Mercier O. VATS versus open thoracotomy for lung cancer resection: is the game still running? Eur J Cardiothorac Surg 2022; 62: ezac303.
- Kolařík J, Stolz A, Vachtenheim J et al. Videoasistované a roboticky asistované thorakoskopické plicní lobektomie, naše zkušenosti. Rozhl Chir 2021; 100: 576–583.
- Kolařík J, Tavandžis J, Novysedlák R et al. Robotické plicní segmentektomie, iniciální zkušenosti v České republice. Rozhl Chir 2023; 102: 199–203.
- Tulinský L, Kepičová M, Mitták M et al. Metastatický potenciál nemalobuněčného karcinomu plic kategorie T1a a T1b: analýza v české populaci. Rozhl Chir 2023; 102: 244–250.
- Couñago F, Luna J, Guerrero LL et al. Management of oligometastatic non-small cell lung cancer patients: Current controversies and future directions. World J Clin Oncol 2019; 10: 318–339.
- Lee CY, Cheng YD, Cheng WY et al. The prevalence of anticholinergic drugs and correlation with pneumonia in elderly patients: a population-based study in Taiwan. Int J Environ Res Public Health 2020; 17: 6260.
- Schussler O, Alifano M, Dermine H et al. Postoperative pneumonia after major lung resection. Am J Respir Crit Care Med 2006; 173: 1161–1169.
- Simonsen DF, Søgaard M, Bozi I et al. Risk factors for postoperative pneumonia after lung cancer surgery and impact of pneumonia on survival. Respir Med 2015; 109: 1340–1346.
- Tulinský L, Kepičová M, Ihnát P et al. Radicality and safety of mediastinal lymphadenectomy in lung resection: a comparative analysis of uniportal thoracoscopic, multiportal thoracoscopic, and thoracotomy approaches. Surg Endosc 2023; 37: 9208–9216.
- Seely AJE, Ivanovic J, Threader J et al. Systematic classification of morbidity and mortality after thoracic surgery. Ann Thorac Surg 2010; 90: 936–942.
- Batihan G, Ceylan KC, Usluer O et al. Video-assisted thoracoscopic surgery vs thoracotomy for non-small cell lung cancer greater than 5 cm: is VATS a feasible approach for large tumors? J Cardiothorac Surg 2020; 15: 261.
- Detillon DDEMA, Veen EJ. Postoperative outcome after pulmonary surgery for non-small cell lung cancer in elderly patients. Ann Thorac Surg 2018; 105: 287–293.
- Al-Ameri M, Bergman P, Franco-Cereceda A et al. Video-assisted thoracoscopic versus open thoracotomy lobectomy: a Swedish nationwide cohort study. J Thorac Dis 2018; 10: 3499–3506.
- Guerrera F, Lybéris P, Lausi PO et al. Does morbid obesity influence perioperative outcomes after video-assisted thoracic surgery (VATS) lobectomy for non-small cell lung cancer? Analysis of the Italian VATS group registry. Surg Endosc 2021; 36: 3567–3573.
- Tulinský L, Sengul I, Ihnát P et al. Obesity in cases undergoing the surgical procedure of lung lobectomy: risk or benefit? Rev Assoc Med Bras 2022; 68: 1090–1095.
- Tulinský L, Mitták M, Tomášková H et al. Obesity paradox in patients undergoing lung lobectomy – myth or reality? BMC Surg 2018; 18: 61.
- Paul KJ, Walker RL, Dublin S. Anticholinergic medications and risk of community-acquired pneumonia in elderly adults: a population-based case-control study. J Am Geriatr Soc 2015; 63: 476–485.
Štítky
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistČlánok vyšiel v časopise
Journal of Czech Physicians
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- Metamizole vs. Tramadol in Postoperative Analgesia
- Spasmolytic Effect of Metamizole
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
Najčítanejšie v tomto čísle
- Gene therapy – once just a dream, now a reality
- Ethical dimensions in telemedicine – balancing technology, responsible care, and patient protection
- Renal impairment in monoclonal gammopathies and multiple myeloma
- Risk factors for postoperative pneumonia in patients after lung resection for non-small cell lung cancer – results of a cohort study