Dynamic SPECT and quantification of coronary flow reserve using a CZT camera

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Authors: Milan Kamínek; Iva Metelková; Lenka Henzlová
Authors place of work: Klinika nukleární medicíny, LF UP a FN Olomouc, ČR
Published in the journal: NuklMed 2021;10:58-62
Category: Review Article

Summary

Conventional SPECT on dual-head camera allows relative estimation of myocardial perfusion. However, it can underestimate the extent of disease in patients with multivessel coronary artery disease. Dynamic positron emission tomography (PET) is the standard for quantification of coronary flow reserve (CFR) and it can assist in the identification of multivessel disease. CFR is calculated as a ratio between myocardial blood flow during stress vasodilator hyperaemia and flow at rest. The normal value of CFR is usually ≥ 2. However, perfusion PET tracers are costly, and not widely available. Recently, quantification of CFR has been validated for dynamic SPECT on Cadmium Zinc Telluride (CZT) cameras. Department of nuclear medicine of University Hospital Olomouc is the first laboratory with the licence for CFR SPECT software in the Czech Republic. The aim is to present our first experience with the new technology of dynamic SPECT on CZT camera.

Keywords:

coronary flow reserve – CFR – dynamic SPECT – CZT camera

Zdroje

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