Erdostein in Secretory Otitis Media

Česká verzia

Authors: L. Otruba ¹; Richard Salzman ² ; R. Kellnerová ³; Z. Hornáčková ¹; M. Uhrová ²
Authors place of work: ORL klinika 3. LF UK a FNKV, Praha ¹; Otolaryngologická klinika LF UP a FN Olomouc ²; Angelini Pharma, Česká republika, s. r. o., Brno ³
Published in the journal: Otorinolaryngol Foniatr, 64, 2015, No. 2, pp. 107-110.
Category: Review Article

Summary

Non interventional post registration study dealing with the treatment of otitis media with effusion (OME). Erdosteine (brand name Erdomed) was administered during 2 months in the group of 42 children aged 3-18 years, 11 with cleft palate, 7 with the chronic form of OME. Evaluation was subjective – ear fullness and objective – oto microscopy, audiometry and tympanometry. Clinical effectiveness – subjective evaluation – ear fullness improved in 83 %. Improvement in objective evaluation - middle ear fluid presence in oto microscopy decreased in 81 % of cases, tympanometry – identification of A curve increased in 34 %, B curve decreased in 68 % of patients. Audiometry – finding of normal hearing increased in 22%, and of air - bone gap of 30 or more dB decreased in 13% of patients. Total treatment effectiveness assessed by physicians was very good in 57 %, and sufficient in 22 % of subjects. Safety and tolerance of Erdomed was declared excellent.

Keywords:
otitis media with effusion, Erdosteine, oto microscopy, tympanometry, audiometry

Zdroje

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