Malignant Melanoma Brain Metastasis – Diagnostic Difficulties

Česká verzia

Authors: M. Duba ¹; A. Mrlian ¹; V. Vybíhal ¹; J. Musil ¹; K. Múčková ²
Authors place of work: Neurochirurgická klinika FN, Brno ¹; Ústav patologie FN, Brno ²
Published in the journal: Rozhl. Chir., 2008, roč. 87, č. 12, s. 624-627.
Category: Monothematic special - Original

Summary

Brain metastasis of malignant melanoma pose approximately 10% of all brain metastasis. In event that the primary tumour is unknown, the diagnostics of malignant melanoma metastasis could be difficult [1, 2]. In our case report we present the case of 35-years-old woman, which felt unconscious suddenly, because of high intracranial pressure caused by tumorous brain expansion.

The aim of our report is to describe the course of her disease, because of very late end diagnosis establishment, when the primary tumour was found out randomly.

Key words:
malignant melanoma metastasis – atypic meningeoma – malignant schwannoma

Zdroje

1. Kozler, P. Intrakraniální nádory. Galén-Karolinum, 2007, 277 s.

2. Eichler, A. F., Plotkin, S. R. Brain metastases. Curr. Treat. Options. Neurol., 2008, Jul; 10(4): 308–314.

3. Hofmann, M. A., Coll, S. H., Küchler, I., Kiecker, F., Wurm, R., Sterry, W., Trefzer, U. Prognostic factors and impact of treatment in melanoma brain metastases: better prognosis for women? Dermatology, 2007; 215(1): 10–16.

4. Meier, S., Baumert, B. G., Maier, S., Wellis, G., Burg, G., Seifert, B., Dummer, R. Survival and progostic factors in patient with brain metastase from malignant melanoma. Onkologie, 2004, Apr., 27(2): 145–149.

5. Majer, M., Samlowski, W. E. Management of metastatic melanoma patients with brain metastases. Review. Curr. Oncol. Rep., 2007, Sep; 9(5): 411–416.

6. Náhlovský, J. Neurochirurgie. Galén-Karolinum, 2006, 606 s.

7. Soffietti, R., Rudā, R., Mutani, R. Management of brain metastase. Review. J. Neurol., 2002, Oct; 249(10): 1357–1369.

8. Bafaloukos, D., Gogas, H. The treatment of brain metastase in melanoma patients. Cancer Treat. Rev., 2004, Oct., 30/6: 515–520.

9. McWilliams, R. R., Rao, R. D., Brown, P. D., Link, M. J., Buckner, J. C. Treatment options for brain metastases from melanoma. Review. Expert Rev. Anticancer Ther., 2005, Oct; 5(5): 809–820.

10. Zubovits, J., Buzeny, E., Yu,L., Runcán, L M. HMB-45, S-100, NK1/C3 and MART 1 in metastatic melanoma. Hum. Patol., 35, 2004: 217–223.

11. Mačák, J., Zavřelová, I. Melanoma simulating malignant soft tissue tumor. Česk. Patol., 41, 2005: 146–149.

12. LinksMetellus, P., Bouvier, C., Guyotat, J., Fuentes, S., Jouvet, A., Vasiljevic, A., Giorgi, R., Divour, H., Grisoli, F., Figarella-Branger, D. Solitary fibrous tumors of the central nervous system: clinicopathological and therapeutic considerations of 18 cases. Neurosurgery, 2007, Apr; 60(4): 715–722; discussion 722.