Treatment Outcomes of Colon Cancer Surgery Combined With Radical Lymphadenectomy

Česká verzia

Authors: L. Lipská; V. Visokai; M. Mráček; M. Levý
Authors place of work: Chirurgická klinika 1. LF UK a Fakultní Thomayerovy nemocnice s poliklinikou, Praha přednosta: doc. MUDr. V. Visokai, Ph. D.
Published in the journal: Rozhl. Chir., 2008, roč. 87, č. 5, s. 242-246.
Category: Monothematic special - Original

Summary

The authors analyzed a group of 1281 subjects with colorectal cancer operated and followed up in a single institution from I/1992 to VIII/2007. Colon carcinoma patients were assessed separately (C18). Patients with rectal and rectosigmoid tumors are not included in the presentation. A total of 846 patients were operated for colon carcinomas. In 546 subjects, radical R0 resections were achieved. In the R0 group, the male/female ratio is 315/231, age 29–94 years, the mean age of 69 years. The R0 group stratification by TNM classification was: I 17.8%, II 49.6%, III 24.0%, IV 8.1%, TNMx 0.5%. Irrespective of the TNM staging, three- year, five-year and ten-year survival rates were 80%, 71%, and 51%, resp. The median survival time was 9.85 years. Postoperative morality was 5.5%, morbidity 29.8%, anastomic leak occured in 5.7%. Systematic lymph node dissection up to the apical level, had been gradually introduced as an integral part of the R0 surgery. The aim of the study is to analyze outcomes of the colon carcinoma surgical management, combined with radical lymphadenectomy. Furthermore, effects of the extensive procedure on the postoperative morbidity and moratility rates are analyzed as well.

Key words:
colorectal cancer – colon cancer – surgical management – lymphadenectomy – radicality – R0 resection – survival – morbidity – mortality

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