Current Diagnostic and Treatment Options in Thyroid Carcinoma

Česká verzia

Authors: V. Kavečanský; P. Schwartz ^*; J. Bober; T. Hildebrand; J. Radoňak
Authors place of work: I. chirurgická klinika, Lekárska fakulta Univerzity Pavla Jozefa Šafárika, Košice, Fakultná nemocnica L. Pasteura, Košice, Slovenská republika, prednosta kliniky: prof. MUDr. Jozef Radoňak, CSc. ; SchwartzMed, s. r. o. ^*
Published in the journal: Rozhl. Chir., 2010, roč. 89, č. 6, s. 331-335.
Category: Monothematic special - Original

Summary

Authors evaluated a set of 1182 patients who underwent a surgery for thyroid disease at two workplaces – 1st Surgery Clinic of L. Pasteur Teaching Hospital of Košice and ENT Department of East-Slovak Oncology Institute, a. s. of Košice during 5year period from the point of view of Medullary Thyroid Carcinoma. Of the given number, 9 suffered a confirmed diagnosis of Medullary Thyroid Carcinoma. Incidence and treatment results conform to available publications. The most important elements for successful treatment are considered the early diagnosis and sufficient surgical treatment. The early diagnosis is in hands of GPs and endocrinologists and is the most important regarding the success of treatment. It is useful to direct the surgical treatment into Centres where – regarding rare occurrence, seriousness of disease and specific treatment – the optimum result may be achieved.

Key words:
medullary thyroid carcinoma – surgical treatment

Zdroje

1. Bailey, B. J. Head and neck surgery – otolaryngology. 3.vydanie, Philadelphia, PA, USA, Lippincott Williams & Wilkins, 2001; 1385–1401.

2. Medullary thyroid cancer [on line] internetová encyklopédia Wikipédia, dostupná na: http://en.wikipedia.org./wiki/medullary thyroid cancer.

3. New York Thyroid center, thyroid cancer medullary [on line], dostupné na: http://www.cumc.columbia.edu/dept/thyroid/contact.html.

4. Fleming, J. B., Lea, J. E., Bouvat, M., et al. Surgical strategy for the treatment of medullary thyroid carcinoma. Ann. Surg., 1999; 230: 697–707.

5. Mirallié, E., Iacobone, M., Sebag, F., Henry, J. F. Results of surgical treatment of sporadic medullary thyroid carcinoma following routine measurement of serum calcitonin. J. Cancer Surg., 2004; 30: 790–795.

6. Weber, T., Schilling, T., Frank-Raue, K., et al. Impact of modified radical neck dissection on biochemical cure in medullary thyroid carcinomas. Surgery, 2001; 130: 1044–1049.

7. Gimm, O., Dralle, H. Reoperation in metastasizing medullary thyroid carcinoma: Is a tumor stage-oriented approach justified? Surgery, 1997; 122: 1124–1131.

8. Hyer, S. L., Vini, L., A‘Hern, R., Harmer, C. Medullary thyroid cancer: multivariate analysis of prognostic factors influencing survival. Eur. J. Surg. Oncol., 2000; 26: 686–690.

9. Ruffini, V., Castaldi, P., Treglia, G., Perotti, G., at al. Nuclear medicine procedures in the diagnosis and therapy of medullary thyroid carcinoma. Biomed Pharmacother, 2008; 62: 139–146.