Overall survival: is it an objective endpoint for assessing the quality of surgical treatment for colorectal cancer?
Authors:
L. Martínek 1
; P. Zonča 2; P. Ihnát 1
Authors place of work:
Chirurgická klinika FN Ostrava, přednosta: doc. MUDr. P. Zonča, Ph. D., FRCS
1; Katedra chirurgických oborů LF OU v Ostravě, vedoucí katedry: Doc. MUDr. P. Zonča, Ph. D., FRCS
2
Published in the journal:
Rozhl. Chir., 2013, roč. 92, č. 12, s. 690-693.
Category:
Review
Summary
The monitoring of the quality of surgical treatment is the basic condition for improving the results of medical care. There are various endpoints available to assess the quality of surgical care. Survival time traditionally represents the key parameter for patients with colorectal cancer. Overall survival should not, however, be the only standard accepted measure of surgical care quality. Disease free survival in the early stages, neoadjuvant or adjuvant settings has been validated as a better option. Progression free survival, alone or aggregated with the quality of life, provides a useful, more sensitive parameter for advanced or metastatic colorectal cancer.
The selection of appropriate, valid end-points is the basic prerequisite for improving the quality of surgical care for patients with colorectal cancer.
Key words:
colorectal cancer – disease free survival – progression free survival – overall survival
Zdroje
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Štítky
Surgery Orthopaedics Trauma surgeryČlánok vyšiel v časopise
Perspectives in Surgery
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