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Cerebral salt wasting syndrome (CSWS) – rare case from a surgical department


Authors: D. Šmíd 1;  P. Novák 1;  J. Fichtl 1;  V. Opatrný 1;  D. Bludovský 2
Authors place of work: Chirurgická klinika FN a LF UK v Plzni, přednosta: prof. MUDr. V. Třeška, DrSc. 1;  Neurochirurgické oddělení FN a LF UK v Plzni, primář: MUDr. V. Přibáň, Ph. D. 2
Published in the journal: Rozhl. Chir., 2014, roč. 93, č. 11, s. 549-553.
Category: Case Report

Tato práce byla podpořena grantem MZ IGA NT14227.

Summary

Introduction:
Cerebral salt wasting syndrome (CSWS) is one of several possible causes of the development of hyponatraemia in patients with severe cranial trauma associated with intracranial bleeding and brain oedema. Other possible causes of post-traumatic hyponatraemia include the syndrome of inappropriate antidiuretic hormone secretion (SIADH).

Case history:
The authors present the case of a twenty-five-year-old polytraumatized female patient who was treated in our department and who was diagnosed with cerebral salt wasting syndrome.

Conclusion:
In patients with severe cranial trauma and subsequent hyponatraemia, CSWS should be considered. It is crucial to distinguish between CSWS and SIADH as wrongly selected treatment can have serious or even fatal impacts for a gravely injured patient.

Key words:
CSWS – SIADH – cranial trauma − hyponatraemia


Zdroje

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9. Vylam P, Šutak V, Winkler M. Posttraumatický syndrom cerebrálně podmíněné ztráty vody a iontů (CSWS) – kazuistika. Rozhl Chir 2006;85:269−272.

10. Jabor A, et al. Vnitřní prostředí. Praha, Grada Publishing 2008.

11. Lohani S, Devkota UP. Hyponatremia in patients with traumatic brain injury: Etiology, Incidence and severiry correlation. World neurosurgery 2011;76:355−360.

12. Schwartz WB, Benett W, Curelop S, Bartter FC. A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 1957;23:529−542.

13. Greenberg A, Verbalis JG. Vasopresin receptor antagonist. Kidney International 2006;69:2124−2130.

14. Spasovski G, et al. Clinical practise quideline on diagnosis and treatment of hyponatremia. Nefrol Dial Transplant 2014;29(2):i1−i39.

Štítky
Surgery Orthopaedics Trauma surgery
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