Synovial sarcoma of the liver – case report

Česká verzia

Authors: J. Zajak ; P. Hladík ; R. Lischke
Authors place of work: III. chirurgická klinika 1. LF UK a FNM, přednosta: prof. MUDr. R. Lischke, PhD.
Published in the journal: Rozhl. Chir., 2015, roč. 94, č. 2, s. 78-81.
Category: Case Report

Summary

Synovial sarcoma is malignant mesenchymal fuso-cellular tumor with variable epithelial differentiation. We present the rare case of young female patient with primary synovial sarcoma of the liver. Molecular diagnosis was done by detection of SYT/SSX fusion transcript. Patients with sarcoma should be treated only in high specialized centres.

Key words:
synovial sarcoma of the liver

Zdroje

1. Drozenová J, Povýšil C, Tvrdík D, et al. Primární synoviální sarkom ledviny – popis dvou případů. Čes-slov Patol 2008;1:20−2.

2. Kawai A, Woodruff J, Murray FB, et al. SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma. N Engl J Med 2004;338:153−60.

3. Tvrdík D, Povýšil C, Svatošová J, et al. Molecular diagnosis of synovial sarcoma: RT-PCR detection of SYT-SSX1/2 fusion transcripts in paraffin-embedded tissue. Med Sci Monit 2005;11:1−7.

4. Xiong B, Chen M, Ye F, et al. Primary monophasic synovial sarcoma of the liver in a 13-year-old boy. Pediatr Dev Pathol 2013;16:353−6.

5. Holla P, Hafez GR, Slukvin I, et al. Pathol Res Pract. Synovial sarcoma, a primary liver tumor-a case report. 2006;202:385−7.

6. Fletcher CDM, Bridge, JA, Hogendoorn PCW, et al. World Health Organization classification of tumours of soft tissue and bone. 4th ed. IARC Press, Lyon 2013.

7. ESMO/ European Sarcomas Network Working Group. Soft tissue and visceral sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2012:92−9.

8. Žaloudík J. Chirurgické aspekty léčby sarkomů měkkých tkání. Onkologie 2010;4:297−301.

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Článok vyšiel v časopise

Perspectives in Surgery

2015 Číslo 2

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