Rare malignant tumors of the appendix: surgical treatment of liver metastases − case reports
Authors:
J. Fichtl 1; J. Vodička 1; V. Třeška 1; T. Skalický 1; R. Tupý 2; D. Šmíd 1
Authors place of work:
Chirurgická klinika FN Plzeň a LF Univerzity Karlovy v Plzni, přednosta: prof. MUDr. V. Třeška, DrSc.
1; Klinika zobrazovacích metod FN Plzeň, přednosta: prof. MUDr. B. Kreuzberg, CSc.
2
Published in the journal:
Rozhl. Chir., 2016, roč. 95, č. 11, s. 409-412.
Category:
Case Report
Summary
Introduction:
Tumors of appendix vermiformis are quite rare; they represent only about 0.4% of gastrointestinal tract tumors. They can be both benign and malignant (primary or secondary). Carcinoid is the most common tumor of the appendix. The symptoms can include nothing but non-specific abdominal pain, or on the contrary they can imitate inflammatory acute abdomen. Liver metastases are associated with an advanced stage of malignancy; their surgical treatment is presented rarely in the literature. The aim of this publication is to present two cases with different results of surgical treatment of liver metastases with the primary tumor located in the appendix.
Cases:
The first patient is a 50 years old female who underwent right hepatectomy for liver metastases of Goblet-cell carcinoid of the appendix in 2013 and died six months later due to tumor progression. The second patient is a 58 years old male, still alive, undergoing repeated liver and lung resections and RFA from 2009 due to metastases from appendix carcinoma.
Conclusion:
Examples of dissemination of malignant appendix tumors to the liver need to be evaluated individually. In indicated cases, surgical treatment of liver metastases is justifiable.
Key words:
tumors of appendix − liver metastases − surgical treatment
Zdroje
1. Rutledge RH, Alexander JW. Primary appendiceal malignancies: rare but important. Surgery 1992;111:244−50.
2. Wolf C, Friedl P, Obrist P, et al. Metastasis to the appendix: sonographic appearance and review of the literature. J Ultrasound Med 1999;18:23−5.
3. Tang LH, Shia J, Soslow RA, et al. Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol., 2008;32:1429−43.
4. Chun JM, Lim KH. Gastrointestinal stromal tumor of the vermiform appendix mimicking Meckel‘s diverticulum: Case report with literature review. Int J Surg Case Rep 2016;21:20−2.
5. Sana L, Saber M. Incidental neuroendocrine tumor of the appendiceal base less than 20 mm in diameter: is appendectomy enough? Pan Afr Med J 2015;22:102.
6. McCusker ME, Coté TR, Clegg LX, et al. Primary malignant neoplasms of the appendix: a population-based study from the surveillance, epidemiology and end-results program, 1973–1998. Cancer 2002;94:3307−12.
7. Roy P, Chetty R. Goblet cell carcinoid tumors of the appendix: An overview. World J Gastrointest Oncol 2010;2:251−8.
8. Stancu M, Wu TT, Wallace C, et al. Genetic alterations in goblet cell carcinoids of the vermiform appendix and comparison with gastrointestinal carcinoid tumors. Mod Pathol 2003;16:1189−98.
9. Anderson NH, Somerville JE, Johnston CF, et al. Appendiceal goblet cell carcinoids: a clinicopathological and immunohistochemical study. Histopathology 1991;18:61−5.
10. Shaikh R, Samo KA, Ali A, et al. Mucinous adenocarcinoma of the appendix. J Pak Med Assoc 2011;61:1233−5.
11. Martinez CA, Cutovoi J, Rossi DH, et al. Intramucosal carcinoma of the appendix arising from traditional serrated adenoma. Case Rep Surg 2015; 297450, Epub 2015 Apr. 22.
12. Cummins KA, Russell GB, Votanopoulos KI, et al. Peritoneal dissemination from high-grade appendiceal cancer treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). J Gastrointest Oncol 2016;7:3−9.
Štítky
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