Castleman disease – unusual finding after operation of retroperitoneal tumor of young patient

Česká verzia

Authors: J. Fichtl ¹; V. Třeška ¹; J. Vodička ¹; R. Šulc ¹; O. Hes ²; R. Tupý ³
Authors place of work: Chirurgická klinika LF Univerzity Karlovy a FN Plzeň přednosta: prof. MUDr. V. Třeška, DrSc. ¹; Šiklův ústav patologie, LF v Plzni, Univerzita Karlova v Praze a FN Plzeň přednosta: prof. MUDr. M. Michal ²; Klinika zobrazovacích metod, LF v Plzni, Univerzita Karlova v Praze a FN Plzeň přednosta: prof. MUDr. B. Kreuzberg CSc. ³
Published in the journal: Rozhl. Chir., 2016, roč. 95, č. 2, s. 91-94.
Category: Case Reports

Summary

Castleman disease is rare diagnosis. It was first mentioned in literature in 1954 by doctor Castleman and Lown. It is rare sickness which primary affects lymfatic nodes. There are four histo-morfologic subtypes and two clinic manifestations (uni and mulicentric). Comon clinical picture is simple lymfadenopathy of neck, medistinal a retroperitonal lymfatic nodes. Signs of this disease are heterogenic and depend on histological subtype. Also prognosis depends on type of illness. It should take place as benign diagnosis (unicentric form) but also can be potencionally malignant form which shlould exacerbate to malignant lymfoproliferation (multicentric form). Authors present the case of 29 years old men with clinical manifestation (jundice, intermitent bowel obstruction) of lagre retroperitoneal tumor in subhepatal localization. The treatment was radical surgical extirpation, surgery was without complications. Definitive histological diagnosis was confirmed as hyaline-vascular type of Castleman disease. Because the patient´s clinical form was multicentric, he is now undergoing adjuvant oncological treatment.

Key words:
Castleman disease − reproperitoneal tumor

Zdroje

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