Pulmonary lobectomy in octogenarians with non-small cell lung cancer
Authors:
A. Stolz; J. Šimonek; J. Pozniak; J. Kolařík; J. Schützner; R. Lischke
Authors place of work:
3. chirurgická klinika 1. LF Univerzity Karlovy a FN Motol, Praha
Published in the journal:
Rozhl. Chir., 2018, roč. 97, č. 1, s. 17-20.
Category:
Original articles
Summary
Introduction:
Greater life expectancy and the ageing population have been a worldwide trend. The purpose of our retrospective study was to review outcomes after anatomical resection in octogenarians operated on due to non-small cell lung cancer.
Methods:
The study included 27 patients operated on from 1 January 2001 to 31 December 2016.
Results:
17 men and 10 women with a mean age of 81.5 years (ranging from 80 to 84 years) were involved. The operations included 23 lobectomies (85.1%) and 4 bilobectomies (14.9%). 16 patients had adenocarcinoma (59.2%), 5 patients had squamous cell carcinoma (18.5%) and 4 patients bronchoalveolar carcinoma (14.8 %). The most common comorbidities were hypertension (59.2%) and chronic ischemic heart disease (25.9%). Median hospital stay was 10 days (ranging from 6 to 21 days). Morbidity rate reached 44.4% and 30-day mortality rate was 3.7% (1/27).
Conclusions:
Pulmonary lobectomy for lung cancer in octogenarians is feasible with acceptable morbidity and mortality. Thorough evaluation is necessary to select the most appropriate approach in these patients considered for lung resection. Age alone should not be a contraindication to surgical treatment of lung cancer.
Key words:
lung cancer – lobectomy − octogenarians
Zdroje
1. Zdravotnická ročenka České republiky 1995. Dostupná na: http://www.uzis.cz/publikace/zdravotnicka-rocenka-ceske-republiky-1995. ISBN: 80-86100-01-4.
2. Zdravotnická ročenka České republiky 2014. Dostupná na: http://www.uzis.cz/node/7692. ISSN 1210-9991.
3. Ventuta F, Diso D, Onarati I, et al. Lung cancer in elderly patients. J Thorac Dis 2016;8:S908−14.
4. Sigel K, Bonomi M, Packer S, et al. Effect of age on survival of clinical stage I non-small-cell lung cancer. Ann Surg Oncol 2009;16:1912−7.
5. Brunelli A, Kim A, Berger KI, el al. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013;143:166−90.
6. Brock MV, Kim MP, Hooker CM, et al. Pulmonary resection in octogenarians with stage I nonsmall cell lung cancer: a 22-year experience. Ann Thorac Surg 2004;77:271−7.
7. Dominguez –Ventura A, Allen MS, Cassivi SD, et al. Lung cancer in octogenarians: factors affecting morbidity and mortality after pulmonary resection. Ann Thor Surg 2006;82:1175−9.
8. Berry MF, Onaitis MW, Tong BC, et al. A model for morbidity after lung resection in octogenarians. Eur J Cardiothorac Surg 2011;39:989−94.
9. Feczko A, McKeown E, Wilson JL, et al. Assessing survival and grading the severity of complications in octogenarians undergoing pulmonary lobectomy. Can Respir J 2017. Available from: https://doi.org/10.1155/2017/6294895.
10. McVay CI, Pickens A, Fuller C, et al. VATS anatomic pulmonary resections in octogenarians. Am Surg 2005;71:791−3.
11. Mun M, Kohno T. Video-assisted thoracic surgery for clinical stage I lung cancer in octogenarians. Ann Thorac Surg 2008;85:406−11.
12. Port JL, Mirza FM, Lee PC, et al. Lobectomy in octogenarians with non-small cell lung cancer: ramifications of increasing life expectancy and the benefits of minimally invasive surgery. Ann Thorac Surg 2011;92:1951−57.
13. Bendixen M, Jorgensen O, Kronborg C, et al. Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer. Lancet Oncol 2016;17:836−44.
14. Laursen L, Petersen RH, Hansen HJ, et al. Video-assisted thoracoscopic lobectomy for lung cancer is associated with a lower 30-day morbidity compared with lobectomy by thoracotomy. Eur J Cardiothorac Surg 2016;49:870−5.
Štítky
Surgery Orthopaedics Trauma surgeryČlánok vyšiel v časopise
Perspectives in Surgery
2018 Číslo 1
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Metamizole vs. Tramadol in Postoperative Analgesia
- Spasmolytic Effect of Metamizole
Najčítanejšie v tomto čísle
- Enhanced recovery after colorectal surgery in elderly patients
- Pancreaticoduodenectomy for pancreatic cancer in elderly patients – a single-centre experience
- Pulmonary lobectomy in octogenarians with non-small cell lung cancer
- Plastic surgery of advanced age