#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Gas embolism after periproctal abscess incision and lavage with hydrogen peroxide − a case report Should the use of hydrogen peroxide in surgery be continued?


Authors: A. Zatloukal
Authors place of work: Chirurgická klinika Fakultní nemocnice Ostrava
Published in the journal: Rozhl. Chir., 2021, roč. 100, č. 1, s. 37-39.
Category: Case Report
doi: https://doi.org/10.33699/PIS.2021.100.1.37–39

Summary

Introduction: Hydrogen peroxide is an antiseptic solution still often used in surgical departments for lavage of wounds. Its use is nevertheless linked to an important risk of gas embolism. Such a case report has not yet been published in the Czech literature and awareness of this danger is low among surgeons.

Case report: The author describes the case of gas embolism in a 40 years old patient after lavage of a periproctal abscess incision with 3% hydrogen peroxide. The lavage resulted in a cardiopulmonary arrest with the need of cardiopulmonary resuscitation. Fortunately, the patient recovered without any health consequences.

Conclusion: In the view of important risks and questionable and insufficiently proven benefits it may be the time to possibly reconsider the use of hydrogen peroxide in surgery and replace it with a different antiseptic agent.

Keywords:

hydrogen peroxide − gas embolism − case report


Zdroje
  1. Urban MV, Rath T, Radtke C. Hydrogen peroxide (H(2)O(2)): a review of its use in surgery. Wien Med Wochenschr. 2019;169(9-10):222−225. doi: 10.1007/s10354-017-0610-2. Epub 2017 Nov 16.
  2. McDonnel G, Russell AD. Antiseptics and disinfectants: activity, action and resistance. Clin Microbiol Rev. 1999;12(1):147−179. doi: 10.1128/CMR.12.1.147.
  3. Akuji MA, Chambers DJ. Hydrogen peroxi­de: more harm than good? Br J Anaesth. 2017;118(6):958–959. doi: 10.1093/bja/aex151.
  4. Roth B, Neuenschwander R, Brill F, et al. Effect of antiseptic irrigation on infection rates of traumatic soft tissue wounds: a longitudinal cohort study. J Wound Care. 2017;26:79−87.  doi: 10.12968/jowc.2017.26.3.79.
  5. Hankin FM, Campbell SE, Goldstein SA, et al. Hydrogen peroxide as a topical hemostatic agent. Clin Orthop Relat Res. 1984;186:244−248.
  6. Cho M, Hunt TK, Hussain MZ. Hydrogen peroxide stimulates macrophage vascular endothelial growth factor release. Am J Physiol Heart Circ Physiol. 2001;280:H2357−H63. doi: 10.1152/ajpheart.2001.280.5.
  7. Wilgus TA, Bergdall VK, Dipietro LA, et al. Hydrogen peroxide disrupts scarless fetal wound repair. Wound Repair Regen. 2005;13:513−519. doi: 10.1111/j.1067-1927.2005.00072.x.
  8. O’Toole EA, Goel M, Woodley DT. Hydrogen peroxide inhibits human keratinocyte migration. Dermatol Surg. 1996;22:525−529. doi: 10.1111/j.1524-4725.1996.tb00368.x.
  9. Donati S, Barthélémy A, Boussuges A, et al. Severe air embolism after surgical irrigation with hydrogen peroxide. Presse Med. 1999;28(4):173−175.
  10. Haller G, Faltin-Traub E, Faltin D, et al. Oxygen embolism after hydrogen peroxide irrigation of a vulvar abscess. Br J Anaesth. 2002;88(4):597−599. doi: 10.1093/bja/88.4.597.
  11. Medicines and Healthcare Regulatory Agency: Hydrogen peroxide: reminder of risk of gas embolism when used in surgery (2017) Available from: http://www.gov.uk/drug-safety-update/hydrogen-peroxide-reminder-of-risk-of-gas-embolism-when-used-in-surgery.
Štítky
Surgery Orthopaedics Trauma surgery

Článok vyšiel v časopise

Perspectives in Surgery

Číslo 1

2021 Číslo 1
Najčítanejšie tento týždeň
Najčítanejšie v tomto čísle
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#