Surgery of extrahepatic bile duct cancer – current evidence and recommendations
Authors:
A. Nikov; R. Gürlich
Authors place of work:
Chirurgická klinika Fakultní nemocnice Královské Vinohrady a 3. Lékařské fakulty Univerzity Karlovy, Praha
Published in the journal:
Rozhl. Chir., 2022, roč. 101, č. 9, s. 416-420.
Category:
Review
doi:
https://doi.org/10.33699/PIS.2022.101.9.416–420
Summary
Extrahepatic cholangiocarcinoma is a rare disease with poor prognosis, requiring comprehensive multidisciplinary management. Only radical resection gives hope for long-term survival. Most patients have either an unresectable disease or their condition does not allow for radical surgery. The method of choice for resectable perihilar cholangiocarcinoma is en-block liver resection including the extrahepatic bile duct, or pancreatoduodenectomy for distal cholangiocarcinoma. Hepatopancreatoduodenectomy can be performed in selected patients if the entire hepato-choledochus is affected. Liver transplantation after neoadjuvant treatment can be also considered in highly selected patients with unresectable perihilar cholangiocarcinoma. These procedures are technically demanding, are associated with high morbidity and relevant mortality, and must be concentrated in tertiary hepatobiliary centers. Preoperative optimization (bile duct drainage, nutrition, portal venous embolization, etc.) plays a crucial role in reducing postoperative morbidity and mortality.
Keywords:
cholangiocarcinoma – extrahepatic – Hepatectomy – pancreatoduodenectomy – bile duct
Zdroje
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