Healing of peritoneum, formation of adhesions and the possibilities of their prevention

Česká verzia

Authors: Vít Weinberger ; I. Crha
Authors place of work: Gynekologicko-porodnická klinika LF MU a FN Brno
Published in the journal: Prakt Gyn 2005; 9(1): 9-12

Summary

Peritoneal healing differs from that of skin. When a defect is made in the parietal peritoneum, the entire surface becomes epithelialized simultaneously and not gradually from the borders as in epidermalization of skin wounds. While multiplication and migration of mesothelial cells from the margin of the wound may play a small part in the regenerative process, it cannot play a major role, since new mesothelium develops in the centre of a large wound at the same time as it develops in the centre of as smaller one. Development of intraperitoneal adhesions is a dynamic process whereby surgically traumatized tissues in apposition bind through fibrin bridges, which become organized by wound repair cells, often supporting a rich vascular supply as well as neuronal elements. Surgical technique, anti-adhesion liquids and barriers are used to prevent post-operative adhesions.

Key words:
peritoneal adhesions, peritoneal healing, prevention of adhesions

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